N-(2-(4-(methylamino)-6-(3,4,5-trimethoxyphenylamino)-1,3,5-triazin-2-ylamino)phenyl)methylsulfonamide

Base Information

Chemical Name:N-(2-(4-(methylamino)-6-(3,4,5-trimethoxyphenylamino)-1,3,5-triazin-2-ylamino)phenyl)methylsulfonamide
CAS No.:1448791-46-5
Molecular Formula:C₂₀H₂₅N₇O₅S
Molecular Weight:475.528
Hs Code.:

Synonyms:N-(2-(4-(methylamino)-6-(3,4,5-trimethoxyphenylamino)-1,3,5-triazin-2-ylamino)phenyl)methylsulfonamide

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Chemical Property of N-(2-(4-(methylamino)-6-(3,4,5-trimethoxyphenylamino)-1,3,5-triazin-2-ylamino)phenyl)methylsulfonamide

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Technology Process of N-(2-(4-(methylamino)-6-(3,4,5-trimethoxyphenylamino)-1,3,5-triazin-2-ylamino)phenyl)methylsulfonamide

There total 4 articles about N-(2-(4-(methylamino)-6-(3,4,5-trimethoxyphenylamino)-1,3,5-triazin-2-ylamino)phenyl)methylsulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1448791-08-9
N-(2-(4-chloro-6-(3,4,5-trimethoxyphenylamino)-1,3,5-triazin-2-ylamino)phenyl)methylsulfonamide

: 74-89-5
methylamine

: 1448791-46-5
N-(2-(4-(methylamino)-6-(3,4,5-trimethoxyphenylamino)-1,3,5-triazin-2-ylamino)phenyl)methylsulfonamide

Guidance literature:: In tetrahydrofuran; 1,4-dioxane; at 95 ℃;
DOI:10.1016/j.bmcl.2013.06.038

Reference yield:

: 24313-88-0
3,4,5-Trimethoxyaniline

: 1448791-46-5
N-(2-(4-(methylamino)-6-(3,4,5-trimethoxyphenylamino)-1,3,5-triazin-2-ylamino)phenyl)methylsulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / -10 °C

2: tetrahydrofuran / 20 °C

3: tetrahydrofuran; 1,4-dioxane / 95 °C

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1016/j.bmcl.2013.06.038

Reference yield:

: 37073-18-0
N-(2-aminophenyl)methanesulfonamide

: 1448791-46-5
N-(2-(4-(methylamino)-6-(3,4,5-trimethoxyphenylamino)-1,3,5-triazin-2-ylamino)phenyl)methylsulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 20 °C

2: tetrahydrofuran; 1,4-dioxane / 95 °C

In tetrahydrofuran; 1,4-dioxane;
DOI:10.1016/j.bmcl.2013.06.038