N,N-diethyl-N-{[({[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]-oxy}carbonyl)amino]sulfonyl}ethanaminium inner salt

Base Information

• Chemical Name: N,N-diethyl-N-{[({[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]-oxy}carbonyl)amino]sulfonyl}ethanaminium inner salt
• CAS No.: 883746-25-6
• Molecular Formula: C₁₇H₃₄N₂O₄S
• Molecular Weight: 362.534

Synonyms:N,N-diethyl-N-{[({[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]-oxy}carbonyl)amino]sulfonyl}ethanaminium inner salt

Chemical Property of N,N-diethyl-N-{[({[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]-oxy}carbonyl)amino]sulfonyl}ethanaminium inner salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-diethyl-N-{[({[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]-oxy}carbonyl)amino]sulfonyl}ethanaminium inner salt

There total 2 articles about N,N-diethyl-N-{[({[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]-oxy}carbonyl)amino]sulfonyl}ethanaminium inner salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(-)-mentholsulfamoyl chloride (883746-44-9) + triethylamine (121-44-8) → N,N-diethyl-N-{[({[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]-oxy}carbonyl)amino]sulfonyl}ethanaminium inner salt (883746-25-6)

Guidance literature:

In benzene; at 20 ℃; for 1h;

DOI:10.1055/s-2006-932450

Reference yield:

(-)-menthol (2216-51-5) → N,N-diethyl-N-{[({[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]-oxy}carbonyl)amino]sulfonyl}ethanaminium inner salt (883746-25-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / benzene / 0.5 h / 20 °C

2: 85 percent / benzene / 1 h / 20 °C

In benzene;

DOI:10.1055/s-2006-932450

Reference yield: 70.0%

N,N-diethyl-N-{[({[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]-oxy}carbonyl)amino]sulfonyl}ethanaminium inner salt (883746-25-6) + phenylethane 1,2-diol (93-56-1) → bis((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl) 1-phenylethane-1,2-diyldicarbamate (1225185-03-4)

Guidance literature:

In tetrahydrofuran; Inert atmosphere; Reflux;

DOI:10.1021/jo100212n

upstream raw materials:

(-)-mentholsulfamoyl chloride

triethylamine

(-)-menthol

Downstream raw materials:

2,2-Dioxo-3a,6,7,7a-tetrahydro-2λ⁶-benzo[1,2,3]oxathiazole-3-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

(1R,2R)-benzoic acid 2-(1R,2S,5R)-(2-isopropyl-5-methylcyclohexyloxycarbonylamino)cyclohex-3-enyl ester

(1S,2S)-benzoic acid 2-(1R,2S,5R)-(2-isopropyl-5-methylcyclohexyloxycarbonylamino)cyclohex-3-enyl ester

(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl [(1R,2R)-2-(benzoyloxy)cyclohexyl]carbamate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 883746-25-6 N,N-diethyl-N-{[({[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]-oxy}carbonyl)amino]sulfonyl}ethanaminium inner salt

Send

Send

Metric Ton KG G Pound L ML

Send

Send