rac-11,11,16,16-Tetradeuterio-3-methoxy-6,7:8,9-diseco-1,3,5⁽¹⁰⁾,7-oestratetraen-9,17-dion

Base Information

• Chemical Name: rac-11,11,16,16-Tetradeuterio-3-methoxy-6,7:8,9-diseco-1,3,5⁽¹⁰⁾,7-oestratetraen-9,17-dion
• CAS No.: 80868-78-6
• Molecular Formula: C₁₉H₂₄O₃
• Molecular Weight: 304.366

Synonyms:rac-11,11,16,16-Tetradeuterio-3-methoxy-6,7:8,9-diseco-1,3,5⁽¹⁰⁾,7-oestratetraen-9,17-dion

Chemical Property of rac-11,11,16,16-Tetradeuterio-3-methoxy-6,7:8,9-diseco-1,3,5⁽¹⁰⁾,7-oestratetraen-9,17-dion

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-11,11,16,16-Tetradeuterio-3-methoxy-6,7:8,9-diseco-1,3,5⁽¹⁰⁾,7-oestratetraen-9,17-dion

There total 13 articles about rac-11,11,16,16-Tetradeuterio-3-methoxy-6,7:8,9-diseco-1,3,5⁽¹⁰⁾,7-oestratetraen-9,17-dion which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

rac-3-Methoxy-6,7:8,9-diseco-1,3,5(10),7-oestratetraen-9,17-dion (75863-04-6,75917-50-9,80924-45-4,80952-08-5,84680-71-7,84680-72-8) → rac-11,11,16,16-Tetradeuterio-3-methoxy-6,7:8,9-diseco-1,3,5(10),7-oestratetraen-9,17-dion (80868-78-6)

Guidance literature:

With aluminum oxide; water-d2; In benzene;

DOI:10.1002/jlac.198119811220

Reference yield:

4-methoxysalicylaldehyde (52289-54-0) → rac-11,11,16,16-Tetradeuterio-3-methoxy-6,7:8,9-diseco-1,3,5(10),7-oestratetraen-9,17-dion (80868-78-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 1) Mg / 1) THF; 2) ether, 12 h at room temp.

2: 75 percent / Mn(IV) oxide / petroleum ether / 2 h

4: 81 percent / aluminium oxide, deuterium oxide / benzene

With manganese(IV) oxide; aluminum oxide; water-d2; magnesium; In Petroleum ether; benzene;

DOI:10.1002/jlac.198119811220

Reference yield:

4-bromo-3-methylanisole (27060-75-9) → rac-11,11,16,16-Tetradeuterio-3-methoxy-6,7:8,9-diseco-1,3,5(10),7-oestratetraen-9,17-dion (80868-78-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 1) Mg / 1) THF, 1 h at 50 deg C; 2) THF, -40 deg C to -20 deg C in 2 h

2: 1) Mg / 1) THF; 2) ether, 12 h at room temp.

3: 75 percent / Mn(IV) oxide / petroleum ether / 2 h

5: 81 percent / aluminium oxide, deuterium oxide / benzene

With manganese(IV) oxide; aluminum oxide; water-d2; magnesium; In Petroleum ether; benzene;

DOI:10.1002/jlac.198119811220

upstream raw materials:

rac-3-Methoxy-6,7:8,9-diseco-1,3,5⁽¹⁰⁾,7-oestratetraen-9,17-dion

4-methoxysalicylaldehyde

4-bromo-3-methylanisole

(2Ξ,3SR)-2-Methyl-3-vinylcyclopentan-1-on

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 80868-78-6 rac-11,11,16,16-Tetradeuterio-3-methoxy-6,7:8,9-diseco-1,3,5⁽¹⁰⁾,7-oestratetraen-9,17-dion

Send

Send

Metric Ton KG G Pound L ML

Send

Send