Cbz-L-Ala-D-Gln-O-n-C₅H₁₁

Base Information

• Chemical Name: Cbz-L-Ala-D-Gln-O-n-C₅H₁₁
• CAS No.: 79787-35-2
• Molecular Formula: C₂₁H₃₁N₃O₆
• Molecular Weight: 421.494
• Mol file: 79787-35-2.mol

Synonyms:Cbz-L-Ala-D-Gln-O-n-C₅H₁₁

Chemical Property of Cbz-L-Ala-D-Gln-O-n-C₅H₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cbz-L-Ala-D-Gln-O-n-C₅H₁₁

There total 3 articles about Cbz-L-Ala-D-Gln-O-n-C₅H₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-Glutamin (5959-95-5,26700-71-0) → Cbz-L-Ala-D-Gln-O-n-C5H11 (79787-35-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Et₃N, 2.) dimethylaminopropylamine / 1.) THF, H₂O, 4 deg C, 24 h, 2.) THF, H₂O, 1 h

2: 1.) aq. Cs₂CO₃ / 1.) THF, 2.) DMF, RT, 48 h

With caesium carbonate; triethylamine; 1-amino-3-(dimethylamino)propane;

DOI:10.1021/jm00343a018

Reference yield:

(N-benzyloxycarbonyl)-L-alanine N-hydroxysuccinimide ester (3401-36-3) → Cbz-L-Ala-D-Gln-O-n-C5H11 (79787-35-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Et₃N, 2.) dimethylaminopropylamine / 1.) THF, H₂O, 4 deg C, 24 h, 2.) THF, H₂O, 1 h

2: 1.) aq. Cs₂CO₃ / 1.) THF, 2.) DMF, RT, 48 h

With caesium carbonate; triethylamine; 1-amino-3-(dimethylamino)propane;

DOI:10.1021/jm00343a018

Reference yield:

1-Bromopentane (110-53-2) + Cbz-L-Ala-D-Gln (74842-54-9) → Cbz-L-Ala-D-Gln-O-n-C5H11 (79787-35-2)

Guidance literature:

With caesium carbonate; Yield given. Multistep reaction; 1.) THF, 2.) DMF, RT, 48 h;

DOI:10.1021/jm00343a018

upstream raw materials:

1-Bromopentane

Cbz-L-Ala-D-Gln

D-Glutamin

(N-benzyloxycarbonyl)-L-alanine N-hydroxysuccinimide ester

Downstream raw materials:

1-α-O-benzyl-4,6-O-benzylidene-N-acetylmuramyl-L-alanyl-D-glutamine n-pentyl ester