Fmoc-Glu-[N-[4-(2,4-di(tert-butoxycarbonylamino)butyryl)aminomethyl]benzyl]amide

Base Information

• Chemical Name: Fmoc-Glu-[N-[4-(2,4-di(tert-butoxycarbonylamino)butyryl)aminomethyl]benzyl]amide
• CAS No.: 817562-98-4
• Molecular Formula: C₄₂H₅₃N₅O₁₀
• Molecular Weight: 787.91
• Mol file: 817562-98-4.mol

Synonyms:Fmoc-Glu-[N-[4-(2,4-di(tert-butoxycarbonylamino)butyryl)aminomethyl]benzyl]amide

Chemical Property of Fmoc-Glu-[N-[4-(2,4-di(tert-butoxycarbonylamino)butyryl)aminomethyl]benzyl]amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Fmoc-Glu-[N-[4-(2,4-di(tert-butoxycarbonylamino)butyryl)aminomethyl]benzyl]amide

There total 1 articles about Fmoc-Glu-[N-[4-(2,4-di(tert-butoxycarbonylamino)butyryl)aminomethyl]benzyl]amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-di[(tert-butoxycarbonyl)amino]butyric acid pentafluorophenyl ester (817562-97-3) + N-[N-(9H-fluoren-9-ylmethoxycarbonyl)glutamyl]-1,4-bis(aminomethyl)benzene (817562-96-2) → Fmoc-Glu-[N-[4-(2,4-di(tert-butoxycarbonylamino)butyryl)aminomethyl]benzyl]amide (817562-98-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 22 - 25 ℃; for 2h; pH=~ 7;

Reference yield:

dicyclohexylamine salt of (2S)-2,4-bis[(tert-butoxycarbonyl)amino]butanoic acid (201472-66-4) + Fmoc-Glu-[N-[4-(2,4-di(tert-butoxycarbonylamino)butyryl)aminomethyl]benzyl]amide (817562-98-4) + N-(fluoren-9-ylmethoxycarbonyl)glycine (29022-11-5) + Fmoc-Leu-OH (35661-60-0) + Fmoc-Ile-OH (71989-23-6,251316-98-0) + Fmoc-Tyr(tBu)-OH (71989-38-3,118488-18-9,204384-67-8) + N-(9-fluorenylmethoxycarbonyl)-S-trityl-L-cysteine (103213-32-7,167015-11-4) + N-Fmoc-D-glutamic acid (104091-09-0) + (2S,4R)-4-tert-butoxy-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid (268729-12-0) + Fmoc-L-3-chlorotyrosine (478183-58-3) → C78H111ClN18O20S2 (1023889-17-9)

Guidance literature:

upstream raw materials:

2,4-di[(tert-butoxycarbonyl)amino]butyric acid pentafluorophenyl ester

N-[N-(9H-fluoren-9-ylmethoxycarbonyl)glutamyl]-1,4-bis(aminomethyl)benzene

Downstream raw materials:

C₇₈H₁₁₁ClN₁₈O₂₀S₂