R-(2-oxo-3-((4-(3-oxo-morpholinyl)phenyl)oxazolidin-5-yl))methylmethanesulfonate

Base Information

Chemical Name:R-(2-oxo-3-((4-(3-oxo-morpholinyl)phenyl)oxazolidin-5-yl))methylmethanesulfonate
CAS No.:1117893-61-4
Molecular Formula:C₁₅H₁₈N₂O₇S
Molecular Weight:370.383
Hs Code.:

Synonyms:R-(2-oxo-3-((4-(3-oxo-morpholinyl)phenyl)oxazolidin-5-yl))methylmethanesulfonate

Suppliers and Price of R-(2-oxo-3-((4-(3-oxo-morpholinyl)phenyl)oxazolidin-5-yl))methylmethanesulfonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of R-(2-oxo-3-((4-(3-oxo-morpholinyl)phenyl)oxazolidin-5-yl))methylmethanesulfonate

Chemical Property:

Purity/Quality:: 98% HPLC ^*data from raw suppliers

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Technology Process of R-(2-oxo-3-((4-(3-oxo-morpholinyl)phenyl)oxazolidin-5-yl))methylmethanesulfonate

There total 8 articles about R-(2-oxo-3-((4-(3-oxo-morpholinyl)phenyl)oxazolidin-5-yl))methylmethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1117893-60-3
4-{4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one

: 124-63-0
methanesulfonyl chloride

: 1117893-61-4
R-(2-oxo-3-((4-(3-oxo-morpholinyl)phenyl)oxazolidin-5-yl))methylmethanesulfonate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 4h;

Reference yield: 85.0%

: R-2-hydroxy-3-((4-(3-oxo-morpholinyl)phenyl)amino)propyl methanesulfonate

: 530-62-1
1,1'-carbonyldiimidazole

: 1117893-61-4
R-(2-oxo-3-((4-(3-oxo-morpholinyl)phenyl)oxazolidin-5-yl))methylmethanesulfonate

Guidance literature:: With dmap; In tetrahydrofuran; at 60 ℃; for 12h;

Reference yield:

: 122-98-5
2-Anilinoethanol

: 1117893-61-4
R-(2-oxo-3-((4-(3-oxo-morpholinyl)phenyl)oxazolidin-5-yl))methylmethanesulfonate

Guidance literature:: Multi-step reaction with 6 steps

1: sodium hydroxide / isopropyl alcohol / 0 - 40 °C / pH 7 - 8

2: nitric acid; sulfuric acid / 1 h / -10 °C

3: hydrogen / 5% Pd(II)/C(eggshell) / water; tetrahydrofuran / 6.5 h / 70 °C / 2250.23 Torr

4: sodium hydrogencarbonate / water; acetone / 4 h / 20 °C

5: lithium tert-butoxide / tetrahydrofuran / 24 h / 20 °C

6: triethylamine / dichloromethane / 4 h / 20 °C

With sulfuric acid; hydrogen; nitric acid; sodium hydrogencarbonate; triethylamine; sodium hydroxide; lithium tert-butoxide; 5% Pd(II)/C(eggshell); In tetrahydrofuran; dichloromethane; water; isopropyl alcohol; acetone;