3-(4-phenylacetic acid)-1,2,4,5-tetrazine succinimidyl ester

Base Information

• Chemical Name: 3-(4-phenylacetic acid)-1,2,4,5-tetrazine succinimidyl ester
• CAS No.: 1616668-55-3
• Molecular Formula: C₁₄H₁₁N₅O₄
• Molecular Weight: 313.272

Synonyms:3-(4-phenylacetic acid)-1,2,4,5-tetrazine succinimidyl ester

Chemical Property of 3-(4-phenylacetic acid)-1,2,4,5-tetrazine succinimidyl ester

Chemical Property:

• Boiling Point: 547.5±60.0 °C(Predicted)
• Density: 1.53±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

Tetrazine-NHS ester ≥ 95% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Description: Tetrazine-NHS Ester is a NHS activated tetrazine linker. NHS ester is very reactive with amine containing molecule. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene).

Technology Process of 3-(4-phenylacetic acid)-1,2,4,5-tetrazine succinimidyl ester

There total 1 articles about 3-(4-phenylacetic acid)-1,2,4,5-tetrazine succinimidyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + 2-(4-(1,2,4,5-tetrazin-3-yl)phenyl)acetic acid (1380500-92-4) → 3-(4-phenylacetic acid)-1,2,4,5-tetrazine succinimidyl ester (1616668-55-3)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1002/open.201402000

Reference yield: 67.0%

3-(4-phenylacetic acid)-1,2,4,5-tetrazine succinimidyl ester (1616668-55-3) + C26H45N3O7*3ClH → C36H51N7O8

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In methanol; at 0 - 20 ℃; for 1h;

DOI:10.1021/acs.inorgchem.1c01274

Reference yield: 56.0%

3-(4-phenylacetic acid)-1,2,4,5-tetrazine succinimidyl ester (1616668-55-3) + N-α-(tert-butoxycarbonyl)-L-lysine methyl ester (55757-60-3) → C22H30N6O5

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃;

upstream raw materials:

1-hydroxy-pyrrolidine-2,5-dione

2-(4-(1,2,4,5-tetrazin-3-yl)phenyl)acetic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1616668-55-3 3-(4-phenylacetic acid)-1,2,4,5-tetrazine succinimidyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send