2-(4-methylphenyl)propanal

Base Information

• Chemical Name: 2-(4-methylphenyl)propanal
• CAS No.: 122091-53-6
• Molecular Formula: C₁₀H₁₂O
• Molecular Weight: 148.205
• Mol file: 122091-53-6.mol

Synonyms:2-(4-methylphenyl)propanal

Chemical Property of 2-(4-methylphenyl)propanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 2-(4-methylphenyl)propanal

There total 68 articles about 2-(4-methylphenyl)propanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.4%

1-ethenyl-4-methylbenzene (622-97-9,24936-41-2) + carbon monoxide (201230-82-2) → 2-(4-methylphenyl)propanal (33596-66-6,122091-53-6,122091-55-8,99-72-9) + 3-(4-methylphenyl)propionaldehyde (5406-12-2)

Guidance literature:

With hydrogen; In tetrahydrofuran; at 45 ℃; for 14h; under 51716.2 Torr; regioselective reaction; Autoclave; Inert atmosphere; Green chemistry;

DOI:10.1039/c6ra03859j

Reference yield: 80.0%

4-tolyl iodide (624-31-7) + allyl alcohol (107-18-6) → 2-(4-methylphenyl)propanal (33596-66-6,122091-53-6,122091-55-8,99-72-9) + 3-(4-methylphenyl)propionaldehyde (5406-12-2)

Guidance literature:

With N-benzyl-N,N,N-triethylammonium chloride; palladium diacetate; sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 40 ℃; for 24h;

DOI:10.1016/j.tet.2011.12.060

Reference yield: 75.0%

4-tolyl iodide (624-31-7) + allyl alcohol (107-18-6) → 2-(4-methylphenyl)propanal (33596-66-6,122091-53-6,122091-55-8,99-72-9) + 3-(4-methylphenyl)propionaldehyde (5406-12-2) + 3-(4-methylphenyl)acrylaldehyde (1504-75-2)

Guidance literature:

With dichloro(1,5-cyclooctadiene)palladium(II); sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 85 ℃; for 5h; Reagent/catalyst; Inert atmosphere;

DOI:10.1016/j.tet.2017.03.034

upstream raw materials:

1-methyl-4-isopropyl-1,3-cyclohexadiene

ethyl β-methyl-β-(p-methylphenyl)glycidate

2-(4-methylphenyl)-1,2-propanediol

limonene.

Downstream raw materials:

para-cymen-9-ol

2-p-tolyl-propionaldehyde

2-p-tolyl-propionaldehyde-semicarbazone

α,4-Dimethylbenzenebutanol