BAPA

Base Information

• Chemical Name: BAPA
• CAS No.: 1080530-15-9
• Molecular Formula: C₁₁H₁₉NO₄
• Molecular Weight: 229.276
• Mol file: 1080530-15-9.mol

Synonyms:BAPA

Chemical Property of BAPA

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BAPA

There total 2 articles about BAPA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N-tert-butoxycarbonyl-3-aminopropanol (58885-58-8) + acrylic acid (79-10-7) → BAPA (1080530-15-9)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In ethyl acetate; at 0 ℃; Inert atmosphere;

DOI:10.1039/c1ob05187c

Reference yield: 74.0%

N-tert-butoxycarbonyl-3-aminopropanol (58885-58-8) + acryloyl chloride (814-68-6,25189-84-8) → BAPA (1080530-15-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; Inert atmosphere;

Reference yield: 84.0%

BAPA (1080530-15-9) → acrylic acid 3-aminopropyl ester (91731-97-4)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 20h;

DOI:10.1039/c1ob05187c

upstream raw materials:

N-tert-butoxycarbonyl-3-aminopropanol

acrylic acid

acryloyl chloride

Downstream raw materials:

acrylic acid 3-aminopropyl ester

Refernces

• 1、 Mehlich, Jan,Ravoo, Bart Jan. "Click chemistry by microcontact printing on self-assembled monolayers: A structure-reactivity study by fluorescence microscopy". supporting information; experimental part. p. 4108 - 4115. Retrieved 2011/07/07.