Procaine hydrochloride

Base Information Edit

Chemical Name:Procaine hydrochloride
CAS No.:51-05-8
Deprecated CAS:12663-50-2,138481-13-7,41585-82-4,8023-03-8,41585-82-4,8023-03-8
Molecular Formula:C13H20N2O2^.HCl
Molecular Weight:272.775
Hs Code.:29242990
European Community (EC) Number:200-077-2
NSC Number:757280
UNII:95URV01IDQ
DSSTox Substance ID:DTXSID1044435
Wikidata:Q3680934
NCI Thesaurus Code:C47688
RXCUI:106558
ChEMBL ID:CHEMBL1200841
Mol file:51-05-8.mol

Synonyms:Anuject;Geriocaine;Gerokit;Hewedolor-Procain;Hydrochloride, Procaine;Lophakomp-Procain N;Novocain;Novocaine;Pr?caine chlorhydrate Lavoisier;Procain Braun;Procain curasan;Procain Jenapharm;Procain R?dler;Procain Steigerwald;procain-loges;Procaina Serra;Procaine;Procaine Hydrochloride;R?wo Procain

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Procaine hydrochloride Edit

Chemical Property:

Appearance/Colour:white crystalline powder
Melting Point:155-156 °C(lit.)
Refractive Index:1.5270 (estimate)
Boiling Point:373.6 °C at 760 mmHg
Flash Point:179.8 °C
PSA：55.56000
Density:1.1761 (rough estimate)
LogP:3.15060
Storage Temp.:room temp
Sensitive.:Air Sensitive
Solubility.:Solution S is clear (2.2.1) and colourless (2.2.2, Method II).
Water Solubility.:soluble
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:272.1291556
Heavy Atom Count:18
Complexity:222

Purity/Quality:

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 25-43-36/37/38-23/24/25
Safety Statements: 36/37/39-45-37/39-26

MSDS Files:: Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl
Recent ClinicalTrials:Analgesic Effect of Perineural Fentanyl Additive to Local Anesthetics in Femoral Nerve Block
Description Procaine hydrochloride, also called Novocain, or Novocaine, a topical anesthetic, which can block the nerve fiber conduction temporarilyand has a narcotic effect,strong effect, low toxicity, and non-addictive, but on the skin, mucosal penetration is weak, unsuitable for surface anesthesia, patients are used for infiltration, conduction and spinal anesthesia.The structure of procaine hydrochloride with aromatic primary amino, easy oxidation discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation discoloration. The aqueous solution was stable in pH3.0~5. So preparation of procaine hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and strictly control the sterilization temperature and time. to 100 ℃ steam sterilization 30min circulation is appropriate, and should pay attention to shading, sealed save.The above information is edited by the lookchem of Kui Xiongfeng.
Uses Procaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry.

Technology Process of Procaine hydrochloride

There total 2 articles about Procaine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: