Chemical Property of CID 16057736
Chemical Property:
- Appearance/Colour:white crystalline powder
- Melting Point:155-156 °C(lit.)
- Refractive Index:1.5270 (estimate)
- Boiling Point:373.6 °C at 760 mmHg
- Flash Point:179.8 °C
- PSA：55.56000
- Density:1.1761 (rough estimate)
- LogP:3.15060
- Storage Temp.:room temp
- Sensitive.:Air Sensitive
- Solubility.:Solution S is clear (2.2.1) and colourless (2.2.2, Method II).
- Water Solubility.:soluble
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:7
- Exact Mass:272.1291556
- Heavy Atom Count:18
- Complexity:222
- Purity/Quality:
-
98%, *data from raw suppliers
Procaine Hydrochloride *data from reagent suppliers
Safty Information:
- Pictogram(s):
T
- Hazard Codes:T
- Statements:
25-43-36/37/38-23/24/25
- Safety Statements:
36/37/39-45-37/39-26
- MSDS Files:
-
Total 1 MSDS from other Authors
Useful:
- Canonical SMILES:CC[NH+](CC)CCOC(=O)C1=CC=C(C=C1)N.[Cl-]
-
Description
Procaine hydrochloride, also called Novocain, or Novocaine, a topical anesthetic, which can block the nerve fiber conduction temporarilyand has a narcotic effect,strong effect, low toxicity, and non-addictive, but on the skin, mucosal penetration is weak, unsuitable for surface anesthesia, patients are used for infiltration, conduction and spinal anesthesia.The structure of procaine hydrochloride with aromatic primary amino, easy oxidation discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation discoloration. The aqueous solution was stable in pH3.0~5. So preparation of procaine hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and strictly control the sterilization temperature and time. to 100 ℃ steam sterilization 30min circulation is appropriate, and should pay attention to shading, sealed save.The above information is edited by the lookchem of Kui Xiongfeng.
-
Uses
Procaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in
dentistry.
