Technology Process of 1-13C-2,2-diphenylethanol
There total 2 articles about 1-13C-2,2-diphenylethanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-13C-1,1-diphenylethylene;
With
borane-THF;
In
tetrahydrofuran;
at 20 ℃;
for 4h;
With
sodium hydroxide;
In
tetrahydrofuran;
at 20 ℃;
for 1.5h;
Further stages.;
DOI:10.1021/ja0124562
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: NaH; DMSO / 0.5 h / 20 °C
1.2: 76 percent / dimethylsulfoxide / 24 h / 20 °C
2.1: BH3*THF / tetrahydrofuran / 4 h / 20 °C
2.2: 74 percent / 30percent H2O2; 3.0 M aq. NaOH / tetrahydrofuran / 1.5 h / 20 °C
With
borane-THF; sodium hydride; dimethyl sulfoxide;
In
tetrahydrofuran;
1.2: Wittig reaction;
DOI:10.1021/ja0124562
- Guidance literature:
-
With
oxalyl dichloride; dimethyl sulfoxide; triethylamine;
In
dichloromethane;
at -70 ℃;
for 0.333333h;
DOI:10.1021/ja0124562
