Technology Process of 3-13C-2-methyl-4,4-diphenylcyclohex-2-enone
There total 5 articles about 3-13C-2-methyl-4,4-diphenylcyclohex-2-enone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
ethanol;
at 60 ℃;
for 0.5h;
DOI:10.1021/ja0124562
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: NaH; DMSO / 0.5 h / 20 °C
1.2: 76 percent / dimethylsulfoxide / 24 h / 20 °C
2.1: BH3*THF / tetrahydrofuran / 4 h / 20 °C
2.2: 74 percent / 30percent H2O2; 3.0 M aq. NaOH / tetrahydrofuran / 1.5 h / 20 °C
3.1: 76 percent / (COCl)2; DMSO; Et3N / CH2Cl2 / 0.33 h / -70 °C
4.1: KOH; EtOH / diethyl ether / 14 h / 0 - 20 °C
5.1: 0.15 g / aq. HCl / ethanol / 0.5 h / 60 °C
With
hydrogenchloride; potassium hydroxide; borane-THF; oxalyl dichloride; ethanol; sodium hydride; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane;
1.2: Wittig reaction / 3.1: Swern oxidation / 4.1: Robinson annulation;
DOI:10.1021/ja0124562
- Guidance literature:
-
Multi-step reaction with 2 steps
1: KOH; EtOH / diethyl ether / 14 h / 0 - 20 °C
2: 0.15 g / aq. HCl / ethanol / 0.5 h / 60 °C
With
hydrogenchloride; potassium hydroxide; ethanol;
In
diethyl ether; ethanol;
1: Robinson annulation;
DOI:10.1021/ja0124562
