(2-(1-(4-fluorobenzyl)-5-(4-methoxybenzyl)-1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazin-2-ylamino)ethyl)guanidine

Base Information

Chemical Name:(2-(1-(4-fluorobenzyl)-5-(4-methoxybenzyl)-1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazin-2-ylamino)ethyl)guanidine
CAS No.:1616091-71-4
Molecular Formula:C₂₁H₂₄FN₇O₃
Molecular Weight:441.465
Hs Code.:

Synonyms:(2-(1-(4-fluorobenzyl)-5-(4-methoxybenzyl)-1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazin-2-ylamino)ethyl)guanidine

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Chemical Property of (2-(1-(4-fluorobenzyl)-5-(4-methoxybenzyl)-1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazin-2-ylamino)ethyl)guanidine

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Technology Process of (2-(1-(4-fluorobenzyl)-5-(4-methoxybenzyl)-1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazin-2-ylamino)ethyl)guanidine

There total 6 articles about (2-(1-(4-fluorobenzyl)-5-(4-methoxybenzyl)-1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazin-2-ylamino)ethyl)guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1616092-28-4
C₂₀H₂₂FN₅O₃

: 4023-02-3
1H-pyrazole-1-carboximidamide hydrochloride

: 1616091-71-4
(2-(1-(4-fluorobenzyl)-5-(4-methoxybenzyl)-1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazin-2-ylamino)ethyl)guanidine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 12h;
DOI:10.1016/j.ejmech.2014.05.030

Reference yield:

: 54582-35-3
p-methoxybenzylurea

: 1616091-71-4
(2-(1-(4-fluorobenzyl)-5-(4-methoxybenzyl)-1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazin-2-ylamino)ethyl)guanidine

Guidance literature:: Multi-step reaction with 6 steps

1: 4 h / Reflux

2: sodium methylate / methanol / 0.5 h / 50 °C

3: sodium methylate / methanol / 3 h / 20 °C

4: potassium carbonate / N,N-dimethyl-formamide / 48 h / 20 °C

5: toluene / 12 h / 90 °C

6: N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 20 °C

With sodium methylate; potassium carbonate; N-ethyl-N,N-diisopropylamine; In methanol; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1016/j.ejmech.2014.05.030

Reference yield:

: 1616092-15-9
C₁₉H₁₈FN₃O₃S

: 1616091-71-4
(2-(1-(4-fluorobenzyl)-5-(4-methoxybenzyl)-1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazin-2-ylamino)ethyl)guanidine

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 12 h / 90 °C

2: N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 20 °C

With N-ethyl-N,N-diisopropylamine; In toluene; acetonitrile;
DOI:10.1016/j.ejmech.2014.05.030