9,9-Bis[4-(2-hydroxyethoxy)phenyl]fluorene

Base Information

• Chemical Name: 9,9-Bis[4-(2-hydroxyethoxy)phenyl]fluorene
• CAS No.: 117344-32-8
• Molecular Formula: C29H26O4
• Molecular Weight: 438.523
• Hs Code.: 29094990
• European Community (EC) Number: 672-704-1
• DSSTox Substance ID: DTXSID80396099
• Nikkaji Number: J719.815I
• Wikidata: Q72446749
• ChEMBL ID: CHEMBL336021
• Mol file: 117344-32-8.mol

Synonyms:117344-32-8;Bisphenoxyethanolfluorene;9,9-Bis[4-(2-hydroxyethoxy)phenyl]fluorene;2,2'-(((9H-Fluorene-9,9-diyl)bis(4,1-phenylene))bis(oxy))diethanol;4,4'-(9-Fluorenylidene)bis(2-phenoxyethanol);2-[4-[9-[4-(2-hydroxyethoxy)phenyl]fluoren-9-yl]phenoxy]ethanol;Ethanol, 2,2'-[9H-fluoren-9-ylidenebis(4,1-phenyleneoxy)]bis-;MFCD00216628;BPEF;9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene;C29H26O4;SCHEMBL194556;CHEMBL336021;DTXSID80396099;NQXNYVAALXGLQT-UHFFFAOYSA-N;BCP33309;2,2'-(((9H-Fluorene-9,9-diyl)bis-(4,1-phenylene))bis(oxy))diethanol;AKOS015856806;CS-W013847;SB66382;DS-17929;SY036317;F0447;FT-0751491;9,9-bis[4-(2-hydroxyethoxyl)phenyl]fluorene;D70497;4.4'-(9-fluorenylidene)-bis(2-phenoxyethanol);4.4'-(9-fluorenylidene) bis (2-phenoxyethanol);9,9-Bis[4-(2-hydroxyethoxy)phenyl]fluorene, 98%;J-003608;4,4'-(9-Fluorenylidene)bis(2-phenoxyethanol), 97%;Ethanol,2,2'-[9H-fluoren-9-ylidenebis(4,1-phenyleneoxy)]bis-;2,2'-(((9H-Fluorene-9,9-diyl)bis(4,1-phenylene))-bis(oxy))diethanol;2,2'-(4,4'-(9H-fluorene-9,9-diyl)bis(4,1-phenylene))bis(oxy)diethanol;2-(4-{9-[4-(2-hydroxyethoxy)phenyl]-9H-fluoren-9-yl}phenoxy)ethan-1-ol;4,4 inverted exclamation mark -(9-Fluorenylidene)bis(2-phenoxyethanol);2,2'-(((9H-fluorene-9,9-diyl)bis(4,1-phenylene))bis(oxy))bis(ethan-1-ol)

Chemical Property of 9,9-Bis[4-(2-hydroxyethoxy)phenyl]fluorene

Chemical Property:

• Melting Point: 117-120 °C(lit.)
• Boiling Point: 610.7 °C at 760 mmHg
• PKA: 13.95±0.10(Predicted)
• Flash Point: 323.1 °C
• PSA: 58.92000
• Density: 1.248 g/cm³
• LogP: 4.79190
• Storage Temp.: 2-8°C
• Water Solubility.: Insoluble in water
• XLogP3: 5.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 438.18310931
• Heavy Atom Count: 33
• Complexity: 540

Purity/Quality:

99.5% ^*data from raw suppliers

2,2''-(((9H-Fluorene-9,9-diyl)bis(4,1-phenylene))bis(oxy))diethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 37
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3C2(C4=CC=C(C=C4)OCCO)C5=CC=C(C=C5)OCCO
• Uses: 4,4′-(9-Fluorenylidene)bis(2-phenoxyethanol) may be used for the following syntheses:poly-(carbotetramethyldisiloxane)s, containing poly[oxy{4,4′-(9-fluorenylidene)bis(2-phenoxyethylene)}oxytetramethyldisiloxane] (a fluorescent aromatic chromophore group)poly[oxy(arylene)oxy(tetramethyldisilylene)]s, containing fluorescent aromatic chromophore groups in the polymer main chain, via melt copolymerization reaction with 1,2-bis(diethylamino)tetramethyldisilane

Technology Process of 9,9-Bis[4-(2-hydroxyethoxy)phenyl]fluorene

There total 9 articles about 9,9-Bis[4-(2-hydroxyethoxy)phenyl]fluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

2-Phenoxyethanol (122-99-6,56257-90-0,9004-78-8) + 9-fluorenone (486-25-9,952573-42-1) → 9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene (117344-32-8)

Guidance literature:

With sulfuric acid; ethanethiol; for 12h; Reagent/catalyst; Reflux;

Reference yield: 91.5%

oxirane (75-21-8,99932-75-9) + 9,9-bis(4-hydroxyphenyl)fluorene (3236-71-3) → 9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene (117344-32-8)

Guidance literature:

With potassium hydroxide; In water; isopropyl alcohol; at 30 - 65 ℃; for 6.83333h; Solvent; Temperature; Reagent/catalyst;

Reference yield: 75.0%

[1,3]-dioxolan-2-one (96-49-1) + 9,9-bis(4-hydroxyphenyl)fluorene (3236-71-3) → 9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene (117344-32-8)

Guidance literature:

With potassium fluoride; In N,N-dimethyl-formamide; for 4h; Inert atmosphere; Reflux;

upstream raw materials:

2-Phenoxyethanol

9-fluorenone

oxirane

9,9-bis(4-hydroxyphenyl)fluorene

Downstream raw materials:

9,9-bis[4-(2-acryloyloxyethoxy)phenyl]fluorene

9,9-bis[4-(2,3-epoxypropoxyethoxy)phenyl]fluorene

Refernces

• 1、 Hiroki, Kazuaki,Morii, Nahoko,Yamashita, Hiroshi,Sugiyama, Jun-Ichi. "Efficient microwave-assisted synthesis of 9,9-bis[4-(2-hydroxyethoxy) phenyl]fluorene from 9-fluorenone and 2-phenoxyethanol". . p. 4407 - 4413. Retrieved 2007.
• 2、 -. "A fluorene skeleton fragrant ether class compound preparation method (by machine translation)". Paragraph 0031-0040; 0049-0052. . Retrieved 2018/12/13.
• 3、 -. "9, 9 - bis (4 - (2 - hydroxyethoxy) phenyl) fluorene in production, and the crystal, and production of the crystal". Paragraph 0024. . Retrieved 2017/07/13.