1-[3-(2-Methyl-[1,3]dioxolan-2-yl)-propyl]-cyclohexa-2,5-dienecarboxylic acid methyl ester

Base Information

• Chemical Name: 1-[3-(2-Methyl-[1,3]dioxolan-2-yl)-propyl]-cyclohexa-2,5-dienecarboxylic acid methyl ester
• CAS No.: 155312-75-7
• Molecular Formula: C₁₅H₂₂O₄
• Molecular Weight: 266.337
• Mol file: 155312-75-7.mol

Synonyms:1-[3-(2-Methyl-[1,3]dioxolan-2-yl)-propyl]-cyclohexa-2,5-dienecarboxylic acid methyl ester

Chemical Property of 1-[3-(2-Methyl-[1,3]dioxolan-2-yl)-propyl]-cyclohexa-2,5-dienecarboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[3-(2-Methyl-[1,3]dioxolan-2-yl)-propyl]-cyclohexa-2,5-dienecarboxylic acid methyl ester

There total 1 articles about 1-[3-(2-Methyl-[1,3]dioxolan-2-yl)-propyl]-cyclohexa-2,5-dienecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5-iodo-2-pentanone ethylene ketal (3695-28-1) + methyl cyclohexa-2,5-diene-1-carboxylate (30889-20-4) → 1-[3-(2-Methyl-[1,3]dioxolan-2-yl)-propyl]-cyclohexa-2,5-dienecarboxylic acid methyl ester (155312-75-7)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at 0 ℃; for 1h;

Reference yield:

1-[3-(2-Methyl-[1,3]dioxolan-2-yl)-propyl]-cyclohexa-2,5-dienecarboxylic acid methyl ester (155312-75-7) → {1-[3-(2-Methyl-[1,3]dioxolan-2-yl)-propyl]-cyclohexa-2,5-dienyl}-methanol (155312-76-8)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 1h; Yield given;

Reference yield:

1-[3-(2-Methyl-[1,3]dioxolan-2-yl)-propyl]-cyclohexa-2,5-dienecarboxylic acid methyl ester (155312-75-7) → 3-tert-butyldiphenylsilyloxymethyl-3-(4-oxopentyl)-1,4-cyclohexadiene (155312-77-9)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether / 1 h / 0 °C

2: imidazole / dimethylformamide / 1 h / 23 °C

With 1H-imidazole; lithium aluminium tetrahydride; In diethyl ether; N,N-dimethyl-formamide;

upstream raw materials:

5-iodo-2-pentanone ethylene ketal

methyl cyclohexa-2,5-diene-1-carboxylate

Downstream raw materials:

{1-[3-(2-Methyl-[1,3]dioxolan-2-yl)-propyl]-cyclohexa-2,5-dienyl}-methanol

3-tert-butyldiphenylsilyloxymethyl-3-(4-oxopentyl)-1,4-cyclohexadiene

3-tert-butyldiphenylsilyloxymethyl-3-(4-trifluoromethanesulfonyloxy-4-pentenyl)-1,4-cyclohexadiene