cis-1,4-Bis(aminomethyl)cyclohexane

Base Information

• Chemical Name: cis-1,4-Bis(aminomethyl)cyclohexane
• CAS No.: 10029-09-1
• Molecular Formula: C8H18 N2
• Molecular Weight: 142.244
• Hs Code.: 2921300090
• Mol file: 10029-09-1.mol

Synonyms:1,4-Cyclohexanebis(methylamine),cis- (8CI); cis-1,4-Bis(aminomethyl)cyclohexane;cis-1,4-Cyclohexanebis(methylamine); cis-1,4-Cyclohexylenebis(methylamine);cis-4-Aminomethylcyclohexylmethylamine

Chemical Property of cis-1,4-Bis(aminomethyl)cyclohexane

Chemical Property:

• Melting Point: -9°C(lit.)
• Refractive Index: 1.4940-1.4980
• Boiling Point: 229.4°Cat760mmHg
• Flash Point: 119.7°C
• PSA: 52.04000
• Density: 0.912g/cm³
• LogP: 2.11080

Purity/Quality:

98%,99%, ^*data from raw suppliers

cis-1,4-Bis(aminomethyl)cyclohexane >98.0%(GC)(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cis-1,4-Bis(aminomethyl)cyclohexane

There total 10 articles about cis-1,4-Bis(aminomethyl)cyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cis-cyclohexane-1,4-dicarbonitrile (6550-96-5) → cis-cyclohexane-1,4-diyldimethanamine (10029-09-1)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; acetic acid anhydride / Hydrogenation

2: aqueous hydrochloric acid

With hydrogenchloride; acetic anhydride; platinum;

Reference yield:

cyclohexane-1,4-dicarbonitrile (10534-13-1) → cis-cyclohexane-1,4-diyldimethanamine (10029-09-1) + trans-1,4-cyclohexane-bis(methylamine) (10029-07-9)

Guidance literature:

With ammonium hydroxide; hydrogen; In butan-1-ol; at 80 ℃; under 7125.71 Torr; Reagent/catalyst; Pressure; Time; Overall yield = 97 %; Autoclave;

Reference yield:

trans-1,4-cyclohexanedicarbonitrile (6550-85-2) → cis-cyclohexane-1,4-diyldimethanamine (10029-09-1) + trans-1,4-cyclohexane-bis(methylamine) (10029-07-9)

Guidance literature:

With ammonium hydroxide; hydrogen; In butan-1-ol; at 80 ℃; for 3h; under 26252.6 Torr; Solvent; Time; Pressure; Temperature; Overall yield = 94.3 %; Autoclave;

upstream raw materials:

cis-1,4-bis-acetylaminomethyl-cyclohexane

cis-cyclohexane-1,4-dicarboxylic acid

(1s,4s)-cyclohexane-1,4-dicarbonyl dichloride

cis-cyclohexane-1,4-dicarbonitrile

Downstream raw materials:

N,N'-(cis-1,4-cyclohexylenebismethyl)-bis[2-hydroxydecylamine]

N,N'-cis-cyclohexane-1,4-diyldimethyl-bis-carbamic acid bis-(2-chloro-ethyl) ester

N_.N'-Dibenzyl-cyclohexan-cis-1.4-bis-methylamin

N.N'-Di-<2-fluor-benzyl>-cyclohexan-cis-1.4-bis-methylamin

Refernces

• 1、 -. "METHOD FOR PRODUCING TRANS-1,4-BIS(AMINOMETHYL)CYCLOHEXANE". Paragraph 0152-0156. . Retrieved 2013/08/28.