N-benzoyl allysine ethylene acetal

Base Information

• Chemical Name: N-benzoyl allysine ethylene acetal
• CAS No.: 226725-71-9
• Molecular Formula: C₁₅H₁₉NO₅
• Molecular Weight: 293.32
• Mol file: 226725-71-9.mol

Synonyms:N-benzoyl allysine ethylene acetal

Chemical Property of N-benzoyl allysine ethylene acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-benzoyl allysine ethylene acetal

There total 2 articles about N-benzoyl allysine ethylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

potassium cyanide + carbon monoxide (201230-82-2) + benzoyl chloride (98-88-4) + ethylene glycol (107-21-1) + crotonaldehyde (123-73-9,4170-30-3) → N-benzoyl allysine ethylene acetal (226725-71-9)

Guidance literature:

ethylene glycol; crotonaldehyde; With tartaric acid; In toluene; for 12h; Reflux; Large scale reaction;

carbon monoxide; With Rh(CO)2(acac); hydrogen; 6,6′-[(3,3′-di-tert-butyl-5,5′-dimethoxy-1,1′-biphenyl-2,2′-diyl)bis(oxy)]bis(di-benzo[d,f][1,3,2]dioxaphosphepin); In tetrahydrofuran; at 80 ℃; under 2250.23 Torr; Inert atmosphere; Large scale reaction;

potassium cyanide; benzoyl chloride; Further stages;

DOI:10.1021/op100258j

Reference yield:

C15H17NO4 (1258790-31-6) → N-benzoyl allysine ethylene acetal (226725-71-9)

Guidance literature:

With sodium hydroxide; In water; for 1h;

DOI:10.1021/op100258j

Reference yield: 30.0%

N-benzoyl allysine ethylene acetal (226725-71-9) → (R)-N-benzoyl allysine ethylene acetal (1258790-30-5) + (S)-2-amino-5-(1,3-dioxolane-2-yl)-pentanoic acid (215054-80-1,170242-34-9)

Guidance literature:

With sodium hydroxide; In water; at 65 ℃; for 5h; pH=7.5; Large scale reaction; Enzymatic reaction;

DOI:10.1021/op100258j

upstream raw materials:

carbon monoxide

benzoyl chloride

ethylene glycol

crotonaldehyde

Downstream raw materials:

(R)-N-benzoyl allysine ethylene acetal

(S)-2-amino-5-(1,3-dioxolane-2-yl)-pentanoic acid

Refernces