Malachite Green Carbinol base

Base Information

• Chemical Name: Malachite Green Carbinol base
• CAS No.: 510-13-4
• Molecular Formula: C23H26 N2 O
• Molecular Weight: 346.472
• Hs Code.: 2922199090
• European Community (EC) Number: 208-109-7
• UNII: 680V7SFB75
• DSSTox Substance ID: DTXSID0060149
• Nikkaji Number: J6.258H
• Wikidata: Q27264186
• Mol file: 510-13-4.mol

Synonyms:Malachite Green Carbinol base;510-13-4;Malachite Green carbinol;Bis(p-(dimethylamino)phenyl)phenylmethanol;Carbinolbase des malachitgruen;BRN 2222125;Malachite Green Base;bis[4-(dimethylamino)phenyl]-phenylmethanol;EINECS 208-109-7;Carbinolbase des malachitgruen [German];UNII-680V7SFB75;C.I. Basic Green 4, carbinol;C23H26N2O;Methanol, bis(p-(dimethylamino)phenyl)phenyl)-;680V7SFB75;alpha,alpha-Bis(p-dimethylaminophenyl)benzyl alcohol;Benzenemethanol, 4-(dimethylamino)-.alpha.-[4-(dimethylamino)phenyl]-.alpha.-phenyl-;p,p'-bis(Dimethylamino)triphenylcarbinol;Benzenemethanol, 4-(dimethylamino)-alpha-(4-(dimethylamino)phenyl)-alpha-phenyl-;4-13-00-02278 (Beilstein Handbook Reference);BENZYL ALCOHOL, alpha,alpha-BIS(p-DIMETHYLAMINOPHENYL)-;4-(Dimethylamino)-alpha-(4-(dimethylamino)phenyl)-alpha-phenyl-benzenemethanol;Methanol, bis[p-(dimethylamino)phenyl]phenyl-;METHANOL, BIS(P-(DIMETHYLAMINO)PHENYL)PHENYL-;4-(Dimethylamino)-alpha-[4-(dimethylamino)phenyl]-alpha-phenyl-benzenemethanol;BENZENEMETHANOL, 4-(DIMETHYLAMINO)-.ALPHA.-(4-(DIMETHYLAMINO)PHENYL)-.ALPHA.-PHENYL-;MFCD00151208;bis[4-(dimethylamino)phenyl]phenylmethan-1-ol;SCHEMBL1450207;DTXSID0060149;CHEBI:188911;HY-D1200;ICCB1_000128;ICCB1_000129;MALACHITE GREEN CARBINOL [MI];AKOS024282599;MALACHITE GREEN (CARBINOL BASE);Malachite Green Carbinol base, 95.0%;SMP2_000062;LS-42723;bis(4-(dimethylamino)phenyl)(phenyl)methanol;CS-0143042;FT-0628109;BIS(P-DIMETHYLAMINOPHENYL)PHENYLMETHANOL;Bis[4-(dimethylamino)phenyl](phenyl)methanol #;P,P'-(N,N-DIMETHYLAMINOTRIPHENYLMETHANOL;Malachite Green Carbinol base, Dye content 90 %;Q27264186;1,1-BIS(4-DIMETHYLAMINOPHENYL)-1-PHENYLMETHANOL;BIS(4-N,N-DIMETHYLAMINOPHENYL)PHENYLMETHYL ALCOHOL;Benzyl alcohol, .alpha.,.alpha.-bis(p-dimethylaminophenyl)-;4-(DIMETHYLAMINO)-.ALPHA.-(4-(DIMETHYLAMINO)PHENYL)-.ALPHA.-PHENYL BENZENEMETHANOL;4-(Dimethylamino)-.alpha.-(4-(dimethylamino)phenyl)-.alpha.-phenyl-benzenemethanol

Chemical Property of Malachite Green Carbinol base

Chemical Property:

• Vapor Pressure: 6.7E-12mmHg at 25°C
• Melting Point: 112-114 °C(lit.)
• Refractive Index: 1.6300 (estimate)
• Boiling Point: 526.2°Cat760mmHg
• PKA: 13.78±0.29(Predicted)
• Flash Point: 268.2°C
• PSA: 26.71000
• Density: 1.131g/cm³
• LogP: 4.10280
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 346.204513457
• Heavy Atom Count: 26
• Complexity: 386

Purity/Quality:

98%,99%, ^*data from raw suppliers

SolventGreen1 ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: S61-60-46-39-36/37-26-2:

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Dyes -> Di- and Triaryl Dyes
• Canonical SMILES: CN(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)N(C)C)O

Technology Process of Malachite Green Carbinol base

There total 39 articles about Malachite Green Carbinol base which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

benzoic acid ethyl ester (93-89-0,99341-95-4) + 4-bromo-N,N-dimethylaniline (586-77-6) → 1,1-bis(4-dimethylaminophenyl)-1-phenyl-methanol (510-13-4)

Guidance literature:

4-bromo-N,N-dimethylaniline; With magnesium; In tetrahydrofuran; Reflux;

benzoic acid ethyl ester; In tetrahydrofuran; at 20 ℃; Reflux;

DOI:10.1002/chem.200902669

Reference yield:

Malachitgruen (569-64-2,38676-32-3) → 1,1-bis(4-dimethylaminophenyl)-1-phenyl-methanol (510-13-4)

Guidance literature:

With water; sodium carbonate;

Reference yield:

benzoic acid benzyl ester (120-51-4) + 4-bromo-N,N-dimethylaniline (586-77-6) → 1,1-bis(4-dimethylaminophenyl)-1-phenyl-methanol (510-13-4)

Guidance literature:

4-bromo-N,N-dimethylaniline; With iodine; magnesium; In tetrahydrofuran; Reflux;

benzoic acid benzyl ester; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

upstream raw materials:

ethanol

bis(4-N,N-dimethylaminophenyl)phenylacetonitrile

benzoic acid ethyl ester

4-bromo-N,N-dimethylaniline

Downstream raw materials:

bis-(p-N,N-dimethylaminophenyl)phenylmethyl methyl ether

4-(4,4'-bis-dimethylamino-trityl)-5-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one

bis-(p-N,N-dimethylaminophenyl)phenylmethyl ethyl ether

formaldehyd

Refernces

• 1、 Samiey, Babak,Zafari, Mahshid. "Kinetics of malachite green fading in water-ethanol-1-propanol ternary mixtures". . p. 32 - 39. Retrieved 2012.
• 2、 Samiey, Babak,Toosi, Ali Raoof. "Kinetics of malachite green fading in alcohol-water binary mixtures". . p. 508 - 518. Retrieved 2010.
• 3、 Dasmandal, Somnath,Mandal, Harasit Kumar,Kundu, Arjama,Mahapatra, Ambikesh. "Kinetic investigations on alkaline fading of malachite green in the presence of micelles and reverse micelles". . p. 123 - 131. Retrieved 2014.
• 4、 -. "Synthesis method of malachite green salt". Paragraph 0043-0055. . Retrieved 2019/12/25.