2-(Trifluoromethyl)acrylic acid

Base Information

Chemical Name:2-(Trifluoromethyl)acrylic acid
CAS No.:381-98-6
Molecular Formula:C4H3F3O2
Molecular Weight:140.062
Hs Code.:29161900
European Community (EC) Number:627-408-7
DSSTox Substance ID:DTXSID70343138
Nikkaji Number:J393.216H
Wikidata:Q72511585
Mol file:381-98-6.mol

Synonyms:2-(trifluoromethyl)acrylic acid;TFMAA

Suppliers and Price of 2-(Trifluoromethyl)acrylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Trifluoromethyl)acrylic Acid
500mg
$ 75.00

TCI Chemical
2-(Trifluoromethyl)acrylic Acid >98.0%(T)
5g
$ 93.00

TCI Chemical
2-(Trifluoromethyl)acrylic Acid >98.0%(T)
25g
$ 279.00

SynQuest Laboratories
2-(Trifluoromethyl)acrylic acid 98%
25 g
$ 95.00

SynQuest Laboratories
2-(Trifluoromethyl)acrylic acid 98%
100 g
$ 395.00

SynQuest Laboratories
2-(Trifluoromethyl)acrylic acid 98%
5 g
$ 25.00

SynQuest Laboratories
2-(Trifluoromethyl)acrylic acid 98%
2 g
$ 15.00

Sigma-Aldrich
2-(Trifluoromethyl)acrylic acid 98%
1g
$ 67.50

Sigma-Aldrich
2-(Trifluoromethyl)acrylic acid 98%
5g
$ 215.00

Matrix Scientific
2-(Trifluoromethyl)propenoic acid 98%
25g
$ 168.00

Total 96 raw suppliers

Chemical Property of 2-(Trifluoromethyl)acrylic acid

Chemical Property:

Appearance/Colour:Light yellow transparent chunks
Vapor Pressure:0.212mmHg at 25°C
Melting Point:51-52 °C(lit.)
Boiling Point:192.6 °C at 760 mmHg
PKA:2.07±0.11(Predicted)
Flash Point:70.3 °C
PSA：37.30000
Density:1.393 g/cm³
LogP:1.18950
Storage Temp.:2-8°C
Water Solubility.:Soluble in water.
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:140.00851382
Heavy Atom Count:9
Complexity:146

Purity/Quality:

99% ^*data from raw suppliers

2-(Trifluoromethyl)acrylic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): C, Xi
Hazard Codes:C,Xi
Statements: 34-36/37/38
Safety Statements: 26-36/37/39-45-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=C(C(=O)O)C(F)(F)F
Uses 2-(Trifluoromethyl)acrylic acid is used as an acidic functional monomer for molecular imprinting of nicotine. And also used in the conventional functional monomer methacrylic acid. 2-(Trifluoromethyl)acrylic acid (TFMAA) is a strong acid functional monomer, which shows a good performance in the solid-phase extraction of domoic acid. It can also be used in the preparation of molecularly imprinted polymers that show diastereoselectivity for cinchona alkaloids.

Technology Process of 2-(Trifluoromethyl)acrylic acid

There total 7 articles about 2-(Trifluoromethyl)acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: zinc copper

: 381-98-6
trifluoromethyacrylic acid

Guidance literature:

Reference yield: 67.0%

: 1514-82-5
2-bromo-3,3,3-trifluoropropene

: 201230-82-2
carbon monoxide

: 381-98-6
trifluoromethyacrylic acid

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; water; triethylamine; In tetrahydrofuran; at 75 - 80 ℃; for 2h; under 26600 Torr;
DOI:10.1055/s-1984-30964