(-)-Alcanfor

Base Information

• Chemical Name: (-)-Alcanfor
• CAS No.: 464-48-2
• Molecular Formula: C10H16O
• Molecular Weight: 152.236
• Hs Code.: 29142910
• European Community (EC) Number: 207-354-7
• UN Number: 2717
• Nikkaji Number: J514.419A
• Mol file: 464-48-2.mol

Synonyms:l-(-)-Camphor;464-48-2;(-)-Alcanfor;s-camphor;EINECS 207-354-7;NA2717;NSC 26351;UN2717;camphor-(1R);SCHEMBL15542393;AKOS015903140;A16423

Chemical Property of (-)-Alcanfor

Chemical Property:

• Appearance/Colour: white crystals
• Vapor Pressure: 4 mm Hg ( 70 °C)
• Melting Point: 177-179 °C(lit.)
• Refractive Index: -44 ° (C=20, EtOH)
• Boiling Point: 207.4 °C at 760 mmHg
• Flash Point: 64.4 °C
• PSA: 17.07000
• Density: 0.982 g/cm³
• LogP: 2.40170
• Storage Temp.: Store below +30°C.
• Water Solubility.: Soluble in water. (0.34 g/L) at 20°C
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 152.120115130
• Heavy Atom Count: 11
• Complexity: 217
• Transport DOT Label: Flammable Solid

Purity/Quality:

99.9% ^*data from raw suppliers

(1S,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi, F
• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 16-26

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Biological Agents -> Plant Oils and Extracts
• Canonical SMILES: CC1(C2CCC1(C(=O)C2)C)C
• Isomeric SMILES: C[C@]12CC[C@@H](C1(C)C)CC2=O
• Uses: (1S,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one also known by its common name as (-)-Camphor is a chiral intermediate of camphor and is used as a flavour additive in foods and sweetners. (1S)-(-)-Camphor is used as chiral intermediate and chiral auxiliary precursor. It is used in the synthesis of high-potency sweeteners. It acts as catalytic agent and petrochemical additive.

Technology Process of (-)-Alcanfor

There total 60 articles about (-)-Alcanfor which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

endo-borneol (464-45-9) → (1S)-camphor (464-48-2,68546-28-1)

Guidance literature:

With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; for 2.5h; Ambient temperature;

DOI:10.1016/0040-4039(94)80038-3

Reference yield: 97.0%

borneol (464-43-7,464-45-9,507-70-0,6627-72-1,10334-13-1,10385-78-1,24393-70-2,124-76-5,16725-71-6) → (1S)-camphor (464-48-2,68546-28-1)

Guidance literature:

With bis(collidine)bromine(I) hexafluorophosphate; In dichloromethane; at 20 ℃; for 2.5h;

DOI:10.1016/S0040-4039(00)01598-7

Reference yield: 95.0%

endo-borneol (791787-82-1) → (1S)-camphor (464-48-2,68546-28-1)

Guidance literature:

With sodium hydrogensulfate monohydrate; iodic acid; In water; acetonitrile; for 5h; Reflux;

DOI:10.14233/ajchem.2013.13480

upstream raw materials:

endo-borneol

d-borneol

Camphor

(-)-(1S,3R,4R)-3-bromocamphor

Downstream raw materials:

(1S,2S,4S)-1,7,7-trimethyl-2-(2'-pyridinyl)bicyclo[2.2.1]heptan-2-ol

(+)-N-(phenylsulfonyl)camphorimine

C₂₅H₄₀N₂O₂S

2-methylisoborneol