N-(1-(cyclohexylmethyl)piperidin-4-yl)-N-((4-methylphenyl)methyl)-4-methoxyphenylacetamide

Base Information

Chemical Name:N-(1-(cyclohexylmethyl)piperidin-4-yl)-N-((4-methylphenyl)methyl)-4-methoxyphenylacetamide
CAS No.:359877-69-3
Molecular Formula:C₂₉H₄₀N₂O₂
Molecular Weight:448.649
Hs Code.:

Synonyms:N-(1-(cyclohexylmethyl)piperidin-4-yl)-N-((4-methylphenyl)methyl)-4-methoxyphenylacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(1-(cyclohexylmethyl)piperidin-4-yl)-N-((4-methylphenyl)methyl)-4-methoxyphenylacetamide

Chemical Property:

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Technology Process of N-(1-(cyclohexylmethyl)piperidin-4-yl)-N-((4-methylphenyl)methyl)-4-methoxyphenylacetamide

There total 15 articles about N-(1-(cyclohexylmethyl)piperidin-4-yl)-N-((4-methylphenyl)methyl)-4-methoxyphenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 359878-14-1
N-((4-methylphenyl)methyl)-N-(piperidin-4-yl)-4-methoxyphenylacetamide

: 2043-61-0
cyclohexanecarbaldehyde

: 359877-69-3
N-(1-(cyclohexylmethyl)piperidin-4-yl)-N-((4-methylphenyl)methyl)-4-methoxyphenylacetamide

Guidance literature:: N-((4-methylphenyl)methyl)-N-(piperidin-4-yl)-4-methoxyphenylacetamide; cyclohexanecarbaldehyde; In ethanol; at 20 ℃; for 48h;

With acetic anhydride; In ethanol; for 24h;

Reference yield:

: 2043-61-0
cyclohexanecarbaldehyde

: AC-90179

: 359877-69-3
N-(1-(cyclohexylmethyl)piperidin-4-yl)-N-((4-methylphenyl)methyl)-4-methoxyphenylacetamide

Guidance literature:: cyclohexanecarbaldehyde; AC-90179; With sodium tetrahydroborate; In ethanol; for 36h;

With acetic acid; In ethanol; for 2h;

Reference yield:

: 104-84-7
para-methylbenzylamine

: 359877-69-3
N-(1-(cyclohexylmethyl)piperidin-4-yl)-N-((4-methylphenyl)methyl)-4-methoxyphenylacetamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid; sodium cyanoborohydride / methanol / 20 h / 20 °C

2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 48 h / 20 °C

3.1: hydrogenchloride / 1,4-dioxane; diethyl ether / 2 h / 20 °C

4.1: solid-supported borohydride / ethanol / 48 h / 20 °C

4.2: 24 h

With hydrogenchloride; sodium cyanoborohydride; acetic acid; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; methanol; diethyl ether; ethanol; dichloromethane;