Technology Process of 5-acetamido-4-ethoxy-2-nitrobenzoyl chloride
There total 7 articles about 5-acetamido-4-ethoxy-2-nitrobenzoyl chloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sulfuryl dichloride;
In
dichloromethane;
at 50 ℃;
for 1h;
DOI:10.3987/COM-11-12343
- Guidance literature:
-
Multi-step reaction with 2 steps
1: nitric acid; acetic acid / 6 h / 25 - 35 °C / Large scale reaction
2: sulfuryl dichloride / dichloromethane / 1 h / 50 °C
With
sulfuryl dichloride; nitric acid; acetic acid;
In
dichloromethane;
DOI:10.3987/COM-11-12343
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sulfuryl dichloride / 8 h / 5 - 65 °C / Large scale reaction
2.1: acetic acid / 3 h / 60 °C / Large scale reaction
3.1: potassium carbonate / N,N-dimethyl-formamide / 6 h / 60 °C / Large scale reaction
4.1: sodium hydroxide / methanol; water / 5 h / 20 °C / Large scale reaction
4.2: 20 °C / pH 2 - 3
5.1: nitric acid; acetic acid / 6 h / 25 - 35 °C / Large scale reaction
6.1: sulfuryl dichloride / dichloromethane / 1 h / 50 °C
With
sulfuryl dichloride; nitric acid; potassium carbonate; acetic acid; sodium hydroxide;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.3987/COM-11-12343
