Technology Process of 5-Acetamido-4-ethoxy-2-nitrobenzoic acid
There total 6 articles about 5-Acetamido-4-ethoxy-2-nitrobenzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
nitric acid; acetic acid;
at 25 - 35 ℃;
for 6h;
Large scale reaction;
DOI:10.3987/COM-11-12343
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sulfuryl dichloride / 8 h / 5 - 65 °C / Large scale reaction
2.1: acetic acid / 3 h / 60 °C / Large scale reaction
3.1: potassium carbonate / N,N-dimethyl-formamide / 6 h / 60 °C / Large scale reaction
4.1: sodium hydroxide / methanol; water / 5 h / 20 °C / Large scale reaction
4.2: 20 °C / pH 2 - 3
5.1: nitric acid; acetic acid / 6 h / 25 - 35 °C / Large scale reaction
With
sulfuryl dichloride; nitric acid; potassium carbonate; acetic acid; sodium hydroxide;
In
methanol; water; N,N-dimethyl-formamide;
DOI:10.3987/COM-11-12343
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydroxide / methanol; water / 5 h / 20 °C / Large scale reaction
1.2: 20 °C / pH 2 - 3
2.1: nitric acid; acetic acid / 6 h / 25 - 35 °C / Large scale reaction
With
nitric acid; acetic acid; sodium hydroxide;
In
methanol; water;
DOI:10.3987/COM-11-12343
