2-Cyano-6-methoxybenzothiazole

Base Information

Chemical Name:2-Cyano-6-methoxybenzothiazole
CAS No.:943-03-3
Molecular Formula:C9H6N2OS
Molecular Weight:190.225
Hs Code.:29341000
Mol file:943-03-3.mol

Synonyms:2-Benzothiazolecarbonitrile,6-methoxy-;6-Methoxy-2-benzothiazolecarbonitrile;NSC 377382;

Suppliers and Price of 2-Cyano-6-methoxybenzothiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
6-methoxybenzo[d]thiazole-2-carbonitrile 96.97%
1g
$ 35.00

Crysdot
6-Methoxybenzo[d]thiazole-2-carbonitrile 95%
25g
$ 653.00

Crysdot
6-Methoxybenzo[d]thiazole-2-carbonitrile 95%
10g
$ 287.00

Matrix Scientific
6-Methoxybenzo[d]thiazole-2-carbonitrile
1g
$ 168.00

Sigma-Aldrich
2-Cyano-6-methoxybenzothiazole 99%
1g
$ 115.00

SynChem
6-Methoxy-benzothiazole-2-carbonitrile 95+%
1 g
$ 59.00

SynChem
6-Methoxy-benzothiazole-2-carbonitrile 95+%
5 g
$ 235.00

SynChem
6-Methoxy-benzothiazole-2-carbonitrile 95+%
10 g
$ 355.00

SynQuest Laboratories
6-Methoxybenzo[d]thiazole-2-carbonitrile
5 g
$ 423.00

SynQuest Laboratories
6-Methoxybenzo[d]thiazole-2-carbonitrile
1 g
$ 149.00

Total 107 raw suppliers

Chemical Property of 2-Cyano-6-methoxybenzothiazole

Chemical Property:

Appearance/Colour:off-white to light yellow crystalline powder
Vapor Pressure:0mmHg at 25°C
Melting Point:129-131 °C(lit.)
Refractive Index:1.654
Boiling Point:334.918 °C at 760 mmHg
PKA:-1.49±0.10(Predicted)
Flash Point:156.353 °C
PSA：74.15000
Density:1.36 g/cm³
LogP:2.17658
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:chloroform: soluble5%, clear, colorless to faintly yellow

Purity/Quality:

99%, ^*data from raw suppliers

6-methoxybenzo[d]thiazole-2-carbonitrile 96.97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi
Statements: 20/21/22-36/37/38
Safety Statements: 26-36-36/37

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-Cyano-6-methoxybenzothiazole is a key intermediate in the synthesis of fireflys’ luciferol, the light emitting chemical. Also a reactant in the preparation of 1,2,4-Oxadiazole EthR inhibitors used in the effort to improve the sensitivity of the human pathogen mycobacterium tuberculosis. Luciferin intermediate. 2-Cyano-6-methoxybenzothiazole has been used in the synthesis of:firefly luciferin via condensation with cysteineluciferin β-glycosides, substrates for novel ultrasensitive enzyme assays

Technology Process of 2-Cyano-6-methoxybenzothiazole

There total 4 articles about 2-Cyano-6-methoxybenzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 75318-49-9
N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-4-methoxyaniline

: 939-69-5
2-cyano-6-hydroxybenzothiazole

: 943-03-3
2-cyano-6-methoxybenzothiazole

Guidance literature:: With pyridine hydrochloride; In sulfolane; at 180 ℃; for 1h;
DOI:10.1039/c4ob02529f

Reference yield: 51.0%

: 104-94-9
4-methoxy-aniline

: 75318-43-3
4,5-dichloro-1,2,3-dithiazolium chloride

: 939-69-5
2-cyano-6-hydroxybenzothiazole

: 943-03-3
2-cyano-6-methoxybenzothiazole

Guidance literature:: 4-methoxy-aniline; 4,5-dichloro-1,2,3-dithiazolium chloride; In sulfolane; at 40 - 180 ℃; for 3.33333h; Sealed tube; Inert atmosphere;

With pyridine hydrochloride; In sulfolane; at 180 ℃; for 1h; Sealed tube; Inert atmosphere;
DOI:10.1039/c4ob02529f