(S)-methyl 4-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)-2,3-difluorobenzoate

Base Information

Chemical Name:(S)-methyl 4-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)-2,3-difluorobenzoate
CAS No.:1372175-49-9
Molecular Formula:C₂₄H₂₂ClF₂NO₄S
Molecular Weight:493.959
Hs Code.:

Synonyms:(S)-methyl 4-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)-2,3-difluorobenzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-methyl 4-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)-2,3-difluorobenzoate

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Technology Process of (S)-methyl 4-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)-2,3-difluorobenzoate

There total 3 articles about (S)-methyl 4-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)-2,3-difluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 863248-27-5
methyl 4-(bromomethyl)-2,3-difluorobenzoate

: 1372175-67-1
(S)-4-chloro-N-(1-phenylpropyl)benzenesulfonamide

: 1372175-49-9
(S)-methyl 4-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)-2,3-difluorobenzoate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield:

: 98-60-2
4-chlorobenzenesulfonyl chloride

: 1372175-49-9
(S)-methyl 4-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)-2,3-difluorobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / tetrahydrofuran / 6 h / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

With potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield:

: 3789-59-1
(R)-1-phenylpropylamine

: 1372175-49-9
(S)-methyl 4-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)-2,3-difluorobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / tetrahydrofuran / 6 h / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

With potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;