Propylboronic acid

Base Information

Chemical Name:Propylboronic acid
CAS No.:17745-45-8
Molecular Formula:C3H9BO2
Molecular Weight:87.9143
Hs Code.:29319090
European Community (EC) Number:681-581-3
NSC Number:518339
UNII:73TJ7U4MDQ
DSSTox Substance ID:DTXSID90325794
Nikkaji Number:J498.342D
Wikidata:Q70000056
Mol file:17745-45-8.mol

Synonyms:Propylboronic acid;n-Propylboronic acid;17745-45-8;1-Propaneboronic acid;Boronic acid, propyl-;Boronic acid, B-propyl-;1-PROPYLBORONIC ACID;MFCD01074564;NSC-518339;Propylboronicacid;1-propaneboronic;N-Propylboronc acd;propyl boronic acid;dihydroxypropylborane;B-Propylboronic acid;73TJ7U4MDQ;C(CC)B(O)O;1-Propylboronic acid, 98%;AMY987;DTXSID90325794;n-Propylboronic acid, AldrichCPR;BDBM152688;NSC518339;1-Propylboronic acid (C3-B(OH)2);AKOS009462782;AB08045;CS-W007470;GS-6753;NSC 518339;SY030878;FT-0600733;P1942;EN300-149189;A812260;J-011282;J-523765

Suppliers and Price of Propylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-PropylboronicAcid
25g
$ 505.00

TRC
N-PropylboronicAcid
5g
$ 130.00

TCI Chemical
Propylboronic Acid (contains varying amounts of Anhydride)
25g
$ 271.00

TCI Chemical
Propylboronic Acid (contains varying amounts of Anhydride)
1g
$ 21.00

TCI Chemical
Propylboronic Acid (contains varying amounts of Anhydride)
5g
$ 55.00

Synthonix
n-Propylboronicacid 95%
25g
$ 50.00

Synthonix
n-Propylboronicacid 95%
1g
$ 15.00

Synthonix
n-Propylboronicacid 95%
5g
$ 20.00

Synthonix
n-Propylboronicacid 95%
100g
$ 140.00

SynQuest Laboratories
n-Propylboronic acid 97%
25 g
$ 130.00

Total 93 raw suppliers

Chemical Property of Propylboronic acid

Chemical Property:

Appearance/Colour:White to light yellow crystal powder
Vapor Pressure:0.461mmHg at 25°C
Melting Point:105-108 °C
Refractive Index:1.388
Boiling Point:170.8 °C at 760 mmHg
PKA:10.31±0.43(Predicted)
Flash Point:57.1 °C
PSA：40.46000
Density:0.925 g/cm³
LogP:-0.13080
Storage Temp.:Refrigerator (+4°C)
Sensitive.:Air Sensitive
Solubility.:DMSO (Slightly), Methanol (Slightly)
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:88.0695597
Heavy Atom Count:6
Complexity:30

Purity/Quality:

98% ^*data from raw suppliers

N-PropylboronicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-22
Safety Statements: 37/39-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(CCC)(O)O
Uses suzuki reaction N-Propylboronic Acid is a chemical reagent used in the synthesis of pharmaceutical agents such as inhibitors of mTOR for use in anti-tumor treatments. Also used to synthesize endothelial lipase inhibitors

Technology Process of Propylboronic acid

There total 14 articles about Propylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 121-43-7,63156-11-6
Trimethyl borate

: 927-77-5
n-propylmagnesium bromide

: 17745-45-8
propylboronic acid

Guidance literature:: DOI:10.1021/ja01268a033

Reference yield: 26.0%

: 121-43-7,63156-11-6
Trimethyl borate

: 7732-18-5
water

: 106-94-5
propyl bromide

: 17745-45-8
propylboronic acid

Guidance literature:: propyl bromide; With magnesium; ethylene dibromide; In tetrahydrofuran; at 0 - 75 ℃; for 2.25h;

Trimethyl borate; In tetrahydrofuran; diethyl ether; at -78 ℃; for 2h;

water; With hydrogenchloride; In tetrahydrofuran; diethyl ether; at 20 ℃; for 0.25h;
DOI:10.1002/ejoc.201900059