(3R)-3-hydroxy-3-phenylpropyl pivalate

Base Information

Chemical Name:(3R)-3-hydroxy-3-phenylpropyl pivalate
CAS No.:96854-35-2
Molecular Formula:C₁₄H₂₀O₃
Molecular Weight:236.311
Hs Code.:

Synonyms:(3R)-3-hydroxy-3-phenylpropyl pivalate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3R)-3-hydroxy-3-phenylpropyl pivalate

Chemical Property:

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Technology Process of (3R)-3-hydroxy-3-phenylpropyl pivalate

There total 6 articles about (3R)-3-hydroxy-3-phenylpropyl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 3282-30-2
pivaloyl chloride

: 103548-16-9
(R)-3-phenyl-1,3-dihydroxypropane

: 96854-35-2
(3R)-3-hydroxy-3-phenylpropyl pivalate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1055/s-2006-950331

Reference yield: 72.0%

: 96854-34-1
(S)-3-phenyl-1,3-propanediol

: 3282-30-2
pivaloyl chloride

: 96854-35-2
2,2-Dimethyl-propionic acid (S)-3-hydroxy-3-phenyl-propyl ester

Guidance literature:: In pyridine;
DOI:10.1016/S0040-4039(01)80815-7

Reference yield:

: 36567-72-3,40620-59-5
(S)-3-hydroxy-3-phenylpropanoic acid

: 96854-35-2
2,2-Dimethyl-propionic acid (S)-3-hydroxy-3-phenyl-propyl ester

Guidance literature:: Multi-step reaction with 3 steps

2: NaBH₄

3: 72 percent / pyridine

With sodium tetrahydroborate; In pyridine;
DOI:10.1016/S0040-4039(01)80815-7