(2S,8S)-5-Oxo-2,8-bis-(9-phenyl-9H-fluoren-9-ylamino)-nonanedioic acid dimethyl ester

Base Information

Chemical Name:(2S,8S)-5-Oxo-2,8-bis-(9-phenyl-9H-fluoren-9-ylamino)-nonanedioic acid dimethyl ester
CAS No.:185121-32-8
Molecular Formula:C₄₉H₄₄N₂O₅
Molecular Weight:740.899
Hs Code.:

Synonyms:(2S,8S)-5-Oxo-2,8-bis-(9-phenyl-9H-fluoren-9-ylamino)-nonanedioic acid dimethyl ester

Suppliers and Price of (2S,8S)-5-Oxo-2,8-bis-(9-phenyl-9H-fluoren-9-ylamino)-nonanedioic acid dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2S,8S)-5-Oxo-2,8-bis-(9-phenyl-9H-fluoren-9-ylamino)-nonanedioic acid dimethyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (2S,8S)-5-Oxo-2,8-bis-(9-phenyl-9H-fluoren-9-ylamino)-nonanedioic acid dimethyl ester

There total 1 articles about (2S,8S)-5-Oxo-2,8-bis-(9-phenyl-9H-fluoren-9-ylamino)-nonanedioic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 185121-50-0
(2S,8S)-5-oxo-2,8-bis-N-[9-(9-phenylfluorenyl)amino]azelate

: 74-88-4
methyl iodide

: 185121-32-8
(2S,8S)-5-Oxo-2,8-bis-(9-phenyl-9H-fluoren-9-ylamino)-nonanedioic acid dimethyl ester

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; for 3h; Ambient temperature;
DOI:10.1021/jo961872f

Reference yield: 81.0%

: 64-17-5
ethanol

: 24424-99-5
di-tert-butyl dicarbonate

: 185121-32-8
(2S,8S)-5-Oxo-2,8-bis-(9-phenyl-9H-fluoren-9-ylamino)-nonanedioic acid dimethyl ester

: 159405-37-5
(3S,6R,9S)-methyl 2-oxo-3--1-azabicyclo<4.3.0>nonane-9-carboxylate

: 159303-54-5
(3S,6S,9S)-methyl 2-oxo-3--1-azabicyclo<4.3.0>nonane-9-carboxylate

: (3S,6S,8aS)-6-tert-Butoxycarbonylamino-5-oxo-octahydro-indolizine-3-carboxylic acid ethyl ester

Guidance literature:: With hydrogen; acetic acid; triethylamine; Yield given. Multistep reaction; 1.) 6 atm, 48 h, 2.) CH₂Cl₂, 2 h;
DOI:10.1021/jo961872f

Reference yield:

: 185121-32-8
(2S,8S)-5-Oxo-2,8-bis-(9-phenyl-9H-fluoren-9-ylamino)-nonanedioic acid dimethyl ester

: (3S,6S,8aS)-5-Oxo-6-[3-((R)-1-phenyl-ethyl)-ureido]-octahydro-indolizine-3-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / 1.) H₂, AcOH, 2.) Et₃N / 1.) 6 atm, 48 h, 2.) CH₂Cl₂, 2 h

2: TFA / CH₂Cl₂ / 4 h

3: Et₃N / tetrahydrofuran / 3 h / Heating

With hydrogen; acetic acid; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo961872f