N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylamine

Base Information

Chemical Name:N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylamine
CAS No.:1226529-15-2
Molecular Formula:C₂₄H₃₁N₃O₃
Molecular Weight:409.528
Hs Code.:

Synonyms:N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylamine

Suppliers and Price of N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylamine

There total 15 articles about N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1226529-17-4
tert-butyl N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylcarbamate

: 1226529-15-2
N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylamine

Guidance literature:: tert-butyl N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylcarbamate; With hydrogenchloride; In ethyl acetate; at 40 ℃; for 1h;

With sodium hydroxide; In water; ethyl acetate;

Reference yield:

: 685886-67-3
[2,6-dimethoxy-4-(methoxymethyl)phenyl]boronic acid

: 1226529-15-2
N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylamine

Guidance literature:: Multi-step reaction with 3 steps

1: barium dihydroxide / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 3 h / 80 °C

2: sodium hydride / DMF (N,N-dimethyl-formamide) / 1 h / 20 °C

3: hydrogenchloride / ethyl acetate / 1 h / 40 °C

With hydrogenchloride; barium dihydroxide; sodium hydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In DMF (N,N-dimethyl-formamide); 1,2-dimethoxyethane; water; ethyl acetate;

Reference yield:

: 475174-64-2
1-(but-1-yn-1-yl)pyridine

: 1226529-15-2
N-cyclobutylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyridin-3-ylamine

Guidance literature:: Multi-step reaction with 9 steps

1.1: dichloromethane / 0.5 h / 0 °C

2.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 20 °C

3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -70 - -60 °C

3.2: 2 h / -70 - 20 °C

4.1: sulfuric acid; nitric acid / 0.5 h / 30 °C

5.1: acetic acid; zinc / ethanol; water / 1 h / 65 °C

6.1: triethylamine / dichloromethane / 15 h / 20 °C

7.1: barium dihydroxide / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 3 h / 80 °C

8.1: sodium hydride / DMF (N,N-dimethyl-formamide) / 1 h / 20 °C

9.1: hydrogenchloride / ethyl acetate / 1 h / 40 °C

With hydrogenchloride; barium dihydroxide; n-butyllithium; sulfuric acid; potassium tert-butylate; nitric acid; sodium hydride; acetic acid; triethylamine; zinc; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); 1,2-dimethoxyethane; ethanol; hexane; dichloromethane; water; ethyl acetate;