(R)-2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 4-methyl-3-phenylpentanoate

Base Information

Chemical Name:(R)-2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 4-methyl-3-phenylpentanoate
CAS No.:1462940-74-4
Molecular Formula:C₂₁H₂₂F₄O₃
Molecular Weight:398.397
Hs Code.:

Synonyms:(R)-2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 4-methyl-3-phenylpentanoate

Suppliers and Price of (R)-2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 4-methyl-3-phenylpentanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 4-methyl-3-phenylpentanoate

Chemical Property:

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Technology Process of (R)-2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 4-methyl-3-phenylpentanoate

There total 4 articles about (R)-2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 4-methyl-3-phenylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 83282-91-1
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl alcohol

: 22573-51-9
(S)-(-)-3-phenyl-4-methylpentanoic acid

: 1462940-74-4
(R)-2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 4-methyl-3-phenylpentanoate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In acetonitrile; at 20 ℃; for 10h;
DOI:10.1016/j.bmcl.2014.04.055

Reference yield:

: 83282-91-1
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl alcohol

: 22573-54-2
(R)-3-phenyl-4-methylpentanoic acid

: 1462940-74-4
(R)-2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 4-methyl-3-phenylpentanoate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In acetonitrile; at 20 ℃; for 10h;
DOI:10.1016/j.bmcl.2014.04.055

Reference yield:

: 1041477-78-4
C₂₂H₃₁NO₃S

: 1462940-74-4
(R)-2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 4-methyl-3-phenylpentanoate

Guidance literature:: Multi-step reaction with 2 steps

1: lithium hydroxide; dihydrogen peroxide / tetrahydrofuran; water / 12 h / 0 °C

2: dmap; dicyclohexyl-carbodiimide / acetonitrile / 10 h / 20 °C

With dmap; dihydrogen peroxide; dicyclohexyl-carbodiimide; lithium hydroxide; In tetrahydrofuran; water; acetonitrile;
DOI:10.1016/j.bmcl.2014.04.055