83282-91-1

Usage

Uses

4-Methoxymethyl-2,3,5,6-tetrafluorobenzyl Alcohol is used as a reagent in the synthesis of Metofluthrin; a potent new synthetic pyrethroid with high vapor activity against mosquitos.

InChI:InChI=1/C9H8F4O2/c1-15-3-5-8(12)6(10)4(2-14)7(11)9(5)13/h14H,2-3H2,1H3

Upstream product

• 942435-98-5 4-methoxymethyl-2,3,5,6-tetrafluorotoluene 
• 62172-93-4 4-(Methoxymethyl)-2,3,5,6-tetrafluorobenzoic acid 
• 802294-64-0 propionic acid 
• 64-19-7 acetic acid 
• 1634-04-4 tert-butyl methyl ether 
• 92339-07-6 2,3,5,6-tetrafluoro-1,4-benzenedimethanol 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 271241-14-6 2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate 
• 1332340-92-7 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl (1R)-trans-3-[(1E)-2-cyano-2-(methylthio)ethenyl]-2,2-dimethylcyclopropane carboxylate 
• 915288-13-0 [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl-(1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylate 
• 1462940-79-9 (S)-2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 4-methyl-3-phenylpentanoate 

Relevant academic research and scientific papers

Synthesis method of 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol

The invention discloses a method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol through 1,4-di(methoxymethyl)-2,3,5,6-tetrafluorobenzene and belongs to the technical field of organic synthesis. The method comprises the following steps: taking the 1,4-di(methoxymethyl)-2,3,5,6-tetrafluorobenzene to react in a mixed solution composed of a sulfuric acid water solution and organiccarboxylic acid; carrying out ester group hydrolysis reaction on an obtained mixture under the action of inorganic alkali; carrying out methylation reaction of hydroxyl under the action of the inorganic alkali; finally, separating and purifying to obtain the 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol and recycling the 1,4-di(methoxymethyl)-2,3,5,6-tetrafluorobenzene. According to the method provided by the invention, resource utilization of the low-value 1,4-di(methoxymethyl)-2,3,5,6-tetrafluorobenzene is realized; meanwhile, the method has the advantages of cheap and easy-to-obtain reaction reagents, moderate reaction conditions, simplicity in operation, high synthesis yield, good product quality and the like, and has very high social and economic value.

A new synthetic route to polyfluorobenzyl alcohol

The synthesis of polyfluorinated benzyl alcohol from pentafluorobenzoic acid has been developed. An economical and effective direct reduction method of polyfluorobenzoic acid by zinc borohydride is described.

TETRAFLUOROTOLUENE COMPOUND, METHOD FOR PRODUCING SAME AND USE THEREOF

A tetrafluorotoluene compound represented by the formula (1): wherein R represents a C1-C6 alkyl group, and a method for producing a tetrafluorotoluene compound represented by the formula (1) which comprises hydrogenating a tetrafluorobenzyl alcohol compound represented by the formula (2): Wherein R represents a C1-C6 alkyl group.

Method for producing 4-methoxymethyl-2,3,5,6-tetrafluorobenzenemethanol

It provides a production method of 4-methoxymethyl-2,3,5,6-tetrafluorobenzenemethanol to allow 2,3,5,6-tetrafluoro-1,4-benzenedimethanol to react with an inorganic base in water, and then add dimethyl sulfate and a water-immiscible organic solvent selected from the group consisting of hydrocarbons and ethers to the reaction mixture, or to allow 2,3,5,6-tetrafluoro-1,4-benzenedimethanol to react with an inorganic base in water and said water-immiscible organic solvent, and then to add dimethyl sulfate to the reaction mixture.

Method for producing 4-methoxymethy1-2,3,5,6-tetrafluorobenzenemethanol

It provides a production method of 4-methoxymethyl-2,3,5,6-tetrafluorobenzenemethanol to allow 2,3,5,6-tetrafluoro-1,4-benzenedimethanol to react with an inorganic base in water, and then add dimethyl sulfate and a water-immiscible organic solvent selected from the group consisting of hydrocarbons and ethers to the reaction mixture, or to allow 2,3,5,6-tetrafluoro-1,4-benzenedimethanol to react with an inorganic base in water and said water-immiscible organic solvent, and then to add dimethyl sulfate to the reaction mixture.

Pyrimidine substituted-2,2-dimethylcyclopropane carboxylates useful for combating insect and acarine pests at a locus

A compound of formula: STR1 wherein R2 represents an α-branched alkyl group containing from 3 to 6 carbon atoms, and R represents either (a) hydroxy, halo or alkoxy of up to six carbon atoms, or (b) the group --OR1 where R1 is the residue of an alcohol of formula R1 OH which forms an insecticidal ester with chrysanthemic acid, permethrin acid or cyhalothrin acid. The compounds have insecticidal and acaricidal properties.