(R,S)-2-Bromo-2-phenylacetic acid (R)-pantolactone ester

Base Information

Chemical Name:(R,S)-2-Bromo-2-phenylacetic acid (R)-pantolactone ester
CAS No.:205748-19-2
Molecular Formula:C₁₄H₁₅BrO₄
Molecular Weight:327.175
Hs Code.:

Synonyms:(R,S)-2-Bromo-2-phenylacetic acid (R)-pantolactone ester

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Chemical Property of (R,S)-2-Bromo-2-phenylacetic acid (R)-pantolactone ester

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Technology Process of (R,S)-2-Bromo-2-phenylacetic acid (R)-pantolactone ester

There total 1 articles about (R,S)-2-Bromo-2-phenylacetic acid (R)-pantolactone ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 4870-65-9,31302-84-8
2-bromophenylacetic acid

: 599-04-2
(R)-Pantolacton

: 205748-19-2
(R,S)-2-Bromo-2-phenylacetic acid (R)-pantolactone ester

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 12h;
DOI:10.1016/j.tetlet.2004.02.004

Reference yield: 92.0%

: 205748-19-2
(R,S)-2-Bromo-2-phenylacetic acid (R)-pantolactone ester

: 103-49-1
dibenzylamine

: 151302-17-9
(S)-2-(N,N-dibenzylamino)-2-phenylacetic acid (R)-pantolactone ester

Guidance literature:: With tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 12h; diastereoselective reaction; Inert atmosphere;
DOI:10.1055/s-0032-1318301