2,2-dimethylpropionic acid 4-({[4-(4-fluorophenyl)-5-formyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester

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Chemical Name:2,2-dimethylpropionic acid 4-({[4-(4-fluorophenyl)-5-formyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester
CAS No.:855249-12-6
Molecular Formula:C₃₄H₃₅FN₂O₄
Molecular Weight:554.661
Hs Code.:

Synonyms:2,2-dimethylpropionic acid 4-({[4-(4-fluorophenyl)-5-formyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester

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Chemical Property of 2,2-dimethylpropionic acid 4-({[4-(4-fluorophenyl)-5-formyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester

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Technology Process of 2,2-dimethylpropionic acid 4-({[4-(4-fluorophenyl)-5-formyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester

There total 1 articles about 2,2-dimethylpropionic acid 4-({[4-(4-fluorophenyl)-5-formyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 855249-11-5
4-(4-fluorophenyl)-5-formyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carboxylic acid 4-hydroxymethylbenzylamide

: 3282-30-2
pivaloyl chloride

: 855249-12-6
2,2-dimethylpropionic acid 4-({[4-(4-fluorophenyl)-5-formyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester

Guidance literature:: 4-(4-fluorophenyl)-5-formyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carboxylic acid 4-hydroxymethylbenzylamide; pivaloyl chloride; With triethylamine; dmap; In dichloromethane; at 0 - 25 ℃; for 4h;

With hydrogenchloride; In diethyl ether; dichloromethane; water;

With sodium hydrogencarbonate; In diethyl ether; dichloromethane; water;

Reference yield: 94.0%

: 855249-12-6
2,2-dimethylpropionic acid 4-({[4-(4-fluorophenyl)-5-formyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester

: 855249-13-7
2,2-dimethylpropionic acid 4-({[4-(4-fluorophenyl)-5-hydroxymethyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester

Guidance literature:: 2,2-dimethylpropionic acid 4-({[4-(4-fluorophenyl)-5-formyl-1-isopropyl-3-phenyl-1H-pyrrole-2-carbonyl]amino}methyl)benzyl ester; With sodium tetrahydroborate; In tetrahydrofuran; methanol; at -10 ℃; for 1h;

With sodium hydrogencarbonate; In tetrahydrofuran; methanol; dichloromethane; water;