7-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-oct-2-ynoic acid ethyl ester

Base Information

Chemical Name:7-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-oct-2-ynoic acid ethyl ester
CAS No.:911849-68-8
Molecular Formula:C₂₆H₃₄O₄Si
Molecular Weight:438.639
Hs Code.:

7-(<i>tert</i>-butyl-diphenyl-silanyloxy)-4-hydroxy-oct-2-ynoic acid ethyl ester

Synonyms:7-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-oct-2-ynoic acid ethyl ester

Suppliers and Price of 7-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-oct-2-ynoic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-oct-2-ynoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-oct-2-ynoic acid ethyl ester

There total 6 articles about 7-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-oct-2-ynoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 203387-36-4
(4S)-4-(tert-butyl(diphenyl)silyloxy)pentanal

: 623-47-2
propynoic acid ethyl ester

: 911849-68-8
7-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-oct-2-ynoic acid ethyl ester

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide;
DOI:10.1016/j.tetlet.2006.07.026

Reference yield:

: (E)-(S)-4-(tert-Butyl-diphenyl-silanyloxy)-pent-2-enoic acid ethyl ester

: 911849-68-8
7-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-oct-2-ynoic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / Pd/C

2: 80 percent / DIBAL-H / -78 °C

3: 72 percent / LDA; HMPA

With N,N,N,N,N,N-hexamethylphosphoric triamide; hydrogen; diisobutylaluminium hydride; lithium diisopropyl amide; palladium on activated charcoal;
DOI:10.1016/j.tetlet.2006.07.026

Reference yield:

: 87696-33-1
(S)-2-(O-tert-butyldiphenylsilyloxy)propanal

: 911849-68-8
7-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-oct-2-ynoic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd/C

2: 80 percent / DIBAL-H / -78 °C

3: 72 percent / LDA; HMPA

With N,N,N,N,N,N-hexamethylphosphoric triamide; hydrogen; diisobutylaluminium hydride; lithium diisopropyl amide; palladium on activated charcoal; 1: Wittig olefination;
DOI:10.1016/j.tetlet.2006.07.026