2,3-Difluorophenylboronic acid

Base Information

Chemical Name:2,3-Difluorophenylboronic acid
CAS No.:121219-16-7
Molecular Formula:C6H5BF2O2
Molecular Weight:157.912
Hs Code.:29163990
European Community (EC) Number:601-759-6,685-121-2
DSSTox Substance ID:DTXSID90370224
Nikkaji Number:J720.576G
Wikidata:Q72463760
Mol file:121219-16-7.mol

Synonyms:2,3-difluorophenylboronic acid

Suppliers and Price of 2,3-Difluorophenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2,3-Difluorophenylboronic acid
10g
$ 365.00

Usbiological
2,3-Difluorophenylboronic acid
10g
$ 365.00

TRC
2,3-Difluorophenylboronic acid
100mg
$ 45.00

TRC
2,3-Difluorophenylboronic acid
500mg
$ 65.00

TCI Chemical
2,3-Difluorophenylboronic Acid (contains varying amounts of Anhydride)
25g
$ 180.00

TCI Chemical
2,3-Difluorophenylboronic Acid (contains varying amounts of Anhydride)
5g
$ 60.00

SynQuest Laboratories
2,3-Difluorobenzeneboronic acid 97%
100 g
$ 472.00

SynQuest Laboratories
2,3-Difluorobenzeneboronic acid 97%
1 g
$ 16.00

SynQuest Laboratories
2,3-Difluorobenzeneboronic acid 97%
25 g
$ 192.00

Sigma-Aldrich
2,3-Difluorophenylboronic acid
25g
$ 166.00

Total 127 raw suppliers

Chemical Property of 2,3-Difluorophenylboronic acid

Chemical Property:

Appearance/Colour:off-white to light beige crystalline powder
Vapor Pressure:0.00257mmHg at 25°C
Melting Point:95 ºC (dec.)
Refractive Index:1.485
Boiling Point:274.8 ºC at 760 mmHg
PKA:7.29±0.58(Predicted)
Flash Point:120ºC
PSA：40.46000
Density:1.35 g/cm³
LogP:-0.35540
Storage Temp.:0-6°C
Solubility.:soluble in Methanol
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:158.0350659
Heavy Atom Count:11
Complexity:134

Purity/Quality:

99% ^*data from raw suppliers

2,3-Difluorophenylboronic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi
Statements: 36/37/38-22
Safety Statements: 37/39-26-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=C(C(=CC=C1)F)F)(O)O
Uses suzuki reaction 2,3-Difluorophenylboronic acid is a useful reagent for the preparation of pharmaceutical and biologically active molecules. Intermediates of Liquid Crystals

Technology Process of 2,3-Difluorophenylboronic acid

There total 10 articles about 2,3-Difluorophenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: C₁₂H₁₇BF₂O₂

: 121219-16-7
(2,3-difluorophenyl)boronic acid

Guidance literature:: With hydrogenchloride; at 20 ℃; for 1h;
DOI:10.1039/a902351h

Reference yield: 96.0%

: C₈H₉BF₂O₂

: 121219-16-7
(2,3-difluorophenyl)boronic acid

Guidance literature:: With hydrogenchloride; In water; for 0.25h; pH=1;

Reference yield: 93.0%

: 5419-55-6
Triisopropyl borate

: 367-11-3
ortho-difluorobenzene

: 121219-16-7
(2,3-difluorophenyl)boronic acid

Guidance literature:: ortho-difluorobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1.16667h; Inert atmosphere;

Triisopropyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;
DOI:10.1039/c8tc06517a