trimethyl-5-(2-(N-methyl-N-(4-nitrostilbene)-4′-amino)-ethoxycarbonyl)amylammonium bromide

Base Information

• Chemical Name: trimethyl-5-(2-(N-methyl-N-(4-nitrostilbene)-4′-amino)-ethoxycarbonyl)amylammonium bromide
• CAS No.: 1431570-41-0
• Molecular Formula: Br*C₂₆H₃₆N₃O₄
• Molecular Weight: 534.494
• Mol file: 1431570-41-0.mol

Synonyms:trimethyl-5-(2-(N-methyl-N-(4-nitrostilbene)-4′-amino)-ethoxycarbonyl)amylammonium bromide

Chemical Property of trimethyl-5-(2-(N-methyl-N-(4-nitrostilbene)-4′-amino)-ethoxycarbonyl)amylammonium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trimethyl-5-(2-(N-methyl-N-(4-nitrostilbene)-4′-amino)-ethoxycarbonyl)amylammonium bromide

There total 4 articles about trimethyl-5-(2-(N-methyl-N-(4-nitrostilbene)-4′-amino)-ethoxycarbonyl)amylammonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-(N-methyl-N-(4-nitrostilbene)-4′-amino)ethyl 6-bromohexanoate (1431570-40-9) + trimethylamine (75-50-3) → trimethyl-5-(2-(N-methyl-N-(4-nitrostilbene)-4′-amino)-ethoxycarbonyl)amylammonium bromide (1431570-41-0)

Guidance literature:

In tetrahydrofuran; at 48 ℃; Reflux; Inert atmosphere;

DOI:10.1021/ma400247h

Reference yield:

4-(N-(2-hydroxyethyl)-N-methylamino)-4′-nitrostilbene (122008-76-8) → trimethyl-5-(2-(N-methyl-N-(4-nitrostilbene)-4′-amino)-ethoxycarbonyl)amylammonium bromide (1431570-41-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: triethylamine / tetrahydrofuran / 0.25 h / 20 °C

1.2: 24 h / 0 - 20 °C

2.1: tetrahydrofuran / 48 °C / Reflux; Inert atmosphere

With triethylamine; In tetrahydrofuran;

DOI:10.1021/ma400247h

Reference yield:

4-nitrobenzeneacetic acid (104-03-0) → trimethyl-5-(2-(N-methyl-N-(4-nitrostilbene)-4′-amino)-ethoxycarbonyl)amylammonium bromide (1431570-41-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: piperidine / Heating

2.1: triethylamine / tetrahydrofuran / 0.25 h / 20 °C

2.2: 24 h / 0 - 20 °C

3.1: tetrahydrofuran / 48 °C / Reflux; Inert atmosphere

With piperidine; triethylamine; In tetrahydrofuran;

DOI:10.1021/ma400247h

upstream raw materials:

2-(N-methyl-N-(4-nitrostilbene)-4′-amino)ethyl 6-bromohexanoate

trimethylamine

4-nitrobenzeneacetic acid

4-(N-methyl-N-hydroxyethylamino)benzaldehyde