2-Hydroxy-4-(trifluoromethyl)pyrimidine

Base Information Edit

Chemical Name:2-Hydroxy-4-(trifluoromethyl)pyrimidine
CAS No.:104048-92-2
Molecular Formula:C5H3F3N2O
Molecular Weight:164.087
Hs Code.:29335990
European Community (EC) Number:623-108-5
DSSTox Substance ID:DTXSID20361286
Nikkaji Number:J2.123.926G
Wikidata:Q72482071
Mol file:104048-92-2.mol

Synonyms:2-Hydroxy-4-(trifluoromethyl)pyrimidine;104048-92-2;4-(trifluoromethyl)pyrimidin-2-ol;4-(trifluoromethyl)pyrimidin-2(1H)-one;2-Hydroxy-4-trifluoromethylpyrimidine;6-(trifluoromethyl)-1H-pyrimidin-2-one;4-(Trifluoromethyl)-2-pyrimidinol;2(1H)-Pyrimidinone, 4-(trifluoromethyl)-;MFCD00192529;Enamine_002404;SCHEMBL1967534;4-(trifluoromethyl)-2-pyrimidol;DTXSID20361286;HMS1400N06;HMS1768P22;BCP21703;CS-D0799;4-trifluoromethyl-2-hydroxypyrimidine;AKOS001012295;AKOS005063546;AC-7379;AS-5573;DS-1472;DS-3137;SB57740;6-(trifluoromethyl)pyrimidin-2(1H)-on;4-(Trifluoromethyl)-2(1H)-pyrimidinone;4-(Trifluoromethyl)pyrimidine-2(1H)-one;BP-13153;SY005948;AM20070690;FT-0642553;H1328;EN300-36298;2-Hydroxy-4-(trifluoromethyl)pyrimidine, 97%;J-509626;Z56767356

Suppliers and Price of 2-Hydroxy-4-(trifluoromethyl)pyrimidine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hydroxy-4-(trifluoromethyl)pyrimidine
25g
$ 500.00

TRC
2-Hydroxy-4-(trifluoromethyl)pyrimidine
10g
$ 210.00

TCI Chemical
2-Hydroxy-4-(trifluoromethyl)pyrimidine >97.0%(GC)(T)
5g
$ 376.00

TCI Chemical
2-Hydroxy-4-(trifluoromethyl)pyrimidine >97.0%(GC)(T)
1g
$ 108.00

SynQuest Laboratories
2-Hydroxy-4-(trifluoromethyl)pyrimidine 97%
5 g
$ 16.00

Oakwood
2-Hydroxy-4-trifluoromethylpyrimidine 95%
25g
$ 50.00

Oakwood
2-Hydroxy-4-trifluoromethylpyrimidine 95%
5g
$ 14.00

Oakwood
2-Hydroxy-4-trifluoromethylpyrimidine 95%
100g
$ 170.00

Medical Isotopes, Inc.
2-Hydroxy-4-(trifluoromethyl)pyrimidine
5 g
$ 850.00

Medical Isotopes, Inc.
2-Hydroxy-4-(trifluoromethyl)pyrimidine
25 g
$ 1800.00

Total 92 raw suppliers

Chemical Property of 2-Hydroxy-4-(trifluoromethyl)pyrimidine Edit

Chemical Property:

Appearance/Colour:light yellow solid
Vapor Pressure:0.00209mmHg at 25°C
Melting Point:223-227 °C(lit.)
Refractive Index:1.484
Boiling Point:281.4 °C at 760 mmHg
PKA:6.12±0.10(Predicted)
Flash Point:124 °C
PSA：46.01000
Density:1.55 g/cm³
LogP:1.20100
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:DMF
XLogP3:-0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:164.01974721
Heavy Atom Count:11
Complexity:241

Purity/Quality:

99% ^*data from raw suppliers

2-Hydroxy-4-(trifluoromethyl)pyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(NC(=O)N=C1)C(F)(F)F
Uses 2-Hydroxy-4-(trifluoromethyl)pyrimidine (cas# 104048-92-2) is a compound useful in organic synthesis.

Technology Process of 2-Hydroxy-4-(trifluoromethyl)pyrimidine

There total 7 articles about 2-Hydroxy-4-(trifluoromethyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 4-trifluoromethylpyrimidine-2-boronic acid

: 104048-92-2
4-(trifluoromethyl)-2-pyrimidinol

Guidance literature:: With hydrazine hydrate; oxygen; caesium carbonate; In water; at 80 ℃; for 10h;

Reference yield: 85.0%

: 59938-06-6,17129-06-5
4-ethoxy-1,1,1-trifluoro-3-butene-2-one

: 57-13-6
urea

: 104048-92-2
6-(trifluoromethyl)pyrimidin-2(1H)-on

Guidance literature:: 4-ethoxy-1,1,1-trifluoro-3-butene-2-one; urea; In methanol; at 15 ℃; for 3.25h; Inert atmosphere; Industry scale;

With hydrogenchloride; In methanol; water; at 60 ℃;