Z-Asp-OMe

Base Information Edit

Chemical Name:Z-Asp-OMe
CAS No.:4668-42-2
Molecular Formula:C13H15NO6
Molecular Weight:281.265
Hs Code.:29224999
European Community (EC) Number:626-932-3
DSSTox Substance ID:DTXSID80427397
Nikkaji Number:J1.412.347D
Wikidata:Q72516040
Mol file:4668-42-2.mol

Synonyms:Z-Asp-OMe;4668-42-2;Z-L-Asp-OMe;Cbz-Asp-OMe;(3S)-4-methoxy-4-oxo-3-(phenylmethoxycarbonylamino)butanoic acid;(S)-3-(((Benzyloxy)carbonyl)amino)-4-methoxy-4-oxobutanoic acid;N-Cbz-L-Aspartic acid 1-methyl ester;MFCD00083277;(3S)-3-{[(BENZYLOXY)CARBONYL]AMINO}-4-METHOXY-4-OXOBUTANOIC ACID;N-Carbobenzoxy-L-aspartic Acid 1-Methyl Ester;(3S)-3-(((benzyloxy)carbonyl)amino)-4-methoxy-4-oxobutanoic acid;1-Methyl N-Carbobenzoxy-L-aspartate;N-Cbz-L-Asp-OMe;1-Methyl N-Cbz-L-aspartate;SCHEMBL1067460;DTXSID80427397;MFFFBNAPQRDRQW-JTQLQIEISA-N;Z-L-aspartic acid |A-methyl ester;AC9386;Cbz-L-aspartic acid |A-methyl ester;AKOS015889948;AM81615;CS-W010044;HY-W009328;N-CBZ L-aspartic acid 1-methyl ester;Z-Asp-OMe, >=98.0% (TLC);DS-13996;M2707;EN300-6503933;N-Benzyloxycarbonyl-L-aspartic acid 1-methyl ester;J-300063;Q-101789;N-(Benzyloxycarbonyl)-L-aspartic acid 1-methyl ester;(S)-2-benzyloxycarbonylamino-succinic acid 1-methyl ester;(S)-3-(Benzyloxycarbonylamino)-4-methoxy-4-oxobutanoic acid

Suppliers and Price of Z-Asp-OMe

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Cbz-L-AsparticAcid1-MethylEster
500mg
$ 75.00

TRC
N-Cbz-L-AsparticAcid1-MethylEster
100mg
$ 60.00

TCI Chemical
1-Methyl N-Carbobenzoxy-L-aspartate >98.0%(HPLC)(T)
5g
$ 38.00

TCI Chemical
1-Methyl N-Carbobenzoxy-L-aspartate >98.0%(HPLC)(T)
25g
$ 104.00

Sigma-Aldrich
Z-Asp-OMe ≥98.0% (TLC)
5g
$ 271.00

Iris Biotech GmbH
Z-L-Asp-OMe
1 g
$ 87.75

Crysdot
Z-Asp-OMe 98%
100g
$ 212.00

chempep
Z-Asp-OMe >=98%
5g
$ 200.00

ChemPep
Z-Asp-OMe ≥98%
25g
$ 695.00

Chem-Impex
Z-L-asparticacidα-methylester,99.5%(ChiralHPLC) 99.5%(ChiralHPLC)
250G
$ 683.20

Total 60 raw suppliers

Chemical Property of Z-Asp-OMe Edit

Chemical Property:

Appearance/Colour:White powder
Vapor Pressure:8.95E-11mmHg at 25°C
Melting Point:89.3oC (dec.)
Refractive Index:1.539
Boiling Point:498.9 °C at 760 mmHg
PKA:4.09±0.19(Predicted)
Flash Point:255.6 °C
PSA：101.93000
Density:1.304 g/cm³
LogP:1.32000
Storage Temp.:−20°C
Solubility.:soluble in Methanol
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:281.08993720
Heavy Atom Count:20
Complexity:351

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Cbz-L-AsparticAcid1-MethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/22-37-41
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C(CC(=O)O)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES:COC(=O)[C@H](CC(=O)O)NC(=O)OCC1=CC=CC=C1

Technology Process of Z-Asp-OMe

There total 20 articles about Z-Asp-OMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 63327-57-1
(2S), 2-benzyloxycarbonylamino-succinic acid 1-methyl ester 4-tertiobutyl ester

: 4668-42-2
(S)-2-benzyloxycarbonylamino-succinic acid 1-methyl ester

Guidance literature:: With trifluoroacetic acid; In dichloromethane; Ambient temperature;
DOI:10.1080/00397919208020852

Reference yield: 93.0%

: 67-56-1
methanol

: 1152-61-0
N-Cbz-L-Asp

: 4668-42-2
(S)-2-benzyloxycarbonylamino-succinic acid 1-methyl ester

Guidance literature:: With tert-butyl methyl ether; Alcalase-cross-linked-enzyme-aggregates; at 50 ℃; for 16h; regioselective reaction; Molecular sieve; Enzymatic reaction;
DOI:10.1016/j.tetlet.2009.03.130