1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-phenethylurea hydrochloride

Base Information

Chemical Name:1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-phenethylurea hydrochloride
CAS No.:1455033-31-4
Molecular Formula:C₂₆H₂₆FN₅O*ClH
Molecular Weight:479.985
Hs Code.:

Synonyms:1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-phenethylurea hydrochloride

Suppliers and Price of 1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-phenethylurea hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-phenethylurea hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-phenethylurea hydrochloride

There total 3 articles about 1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-phenethylurea hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1455035-05-8
1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-phenethylurea

: 1455033-31-4
1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-phenethylurea hydrochloride

Guidance literature:: With hydrogenchloride; In acetonitrile;

Reference yield:

: 1455038-83-1
prop-1-en-2-yl (3-(4-fluoro-2-methyl-5-(((prop-1-en-2-yloxy)carbonyl)amino)phenyl)-2-methyl-1,6-naphthyridin-7-yl)(methyl)carbamate

: 1455033-31-4
1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-phenethylurea hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1-Methylpyrrolidine / 1,4-dioxane / 50 °C

1.2: 20 - 60 °C

2.1: hydrogenchloride / acetonitrile

With 1-Methylpyrrolidine; hydrogenchloride; In 1,4-dioxane; acetonitrile;

Reference yield:

: 1455036-26-6
3-(5-amino-4-fluoro-2-methyl-phenyl)-N, 2-dimethyl-1,6-naphthyridin-7-amine

: 1455033-31-4
1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-phenethylurea hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridine / 1 h / 0 °C

2.1: 1-Methylpyrrolidine / 1,4-dioxane / 50 °C

2.2: 20 - 60 °C

3.1: hydrogenchloride / acetonitrile

With 1-Methylpyrrolidine; pyridine; hydrogenchloride; In 1,4-dioxane; acetonitrile; 1.1: |Schotten-Baumann Reaction;