carbonic acid 5-ethoxycarbonyloxy-7-(4-fluoro-benzyl)-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester ethyl ester

Base Information

Chemical Name:carbonic acid 5-ethoxycarbonyloxy-7-(4-fluoro-benzyl)-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester ethyl ester
CAS No.:907205-56-5
Molecular Formula:C₂₅H₂₁FN₂O₉
Molecular Weight:512.448
Hs Code.:

carbonic acid 5-ethoxycarbonyloxy-7-(4-fluoro-benzyl)-3-methoxy-6,8-dioxo-7,8-dihydro-6<i>H</i>-pyrrolo[3,4-<i>g</i>]quinolin-9-yl ester ethyl ester

Synonyms:carbonic acid 5-ethoxycarbonyloxy-7-(4-fluoro-benzyl)-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester ethyl ester

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Chemical Property of carbonic acid 5-ethoxycarbonyloxy-7-(4-fluoro-benzyl)-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester ethyl ester

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Technology Process of carbonic acid 5-ethoxycarbonyloxy-7-(4-fluoro-benzyl)-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester ethyl ester

There total 2 articles about carbonic acid 5-ethoxycarbonyloxy-7-(4-fluoro-benzyl)-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 871470-94-9
7-(4-fluoro-benzyl)-5,9-dihydroxy-3-methoxy-pyrrolo[3,4-g]quinoline-6,8-dione

: 541-41-3
chloroformic acid ethyl ester

: 907205-56-5
carbonic acid 5-ethoxycarbonyloxy-7-(4-fluoro-benzyl)-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester ethyl ester

Guidance literature:: With pyridine; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.05.018

Reference yield:

: 86386-65-4
1-[(4-fluorophenyl)methyl]-2,5-pyrrolidinedione

: 907205-56-5
carbonic acid 5-ethoxycarbonyloxy-7-(4-fluoro-benzyl)-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 49 percent / NaH / tetrahydrofuran / 0 - 20 °C

2: 90 percent / pyridine / dimethylformamide

With pyridine; sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.05.018