2,7-Naphthalenedicarboxylic acid

Base Information

• Chemical Name: 2,7-Naphthalenedicarboxylic acid
• CAS No.: 2089-89-6
• Molecular Formula: C12H8O4
• Molecular Weight: 216.193
• Hs Code.: 2917399090
• Mol file: 2089-89-6.mol

Synonyms:2,7-NAPHTHALENEDICARBOXYLIC ACID;NAPHTHALENE-2,7-DICARBOXYLICACID;2,7-Naphthalenedicarbxylic acid

Chemical Property of 2,7-Naphthalenedicarboxylic acid

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: >190 °C (sublm)
• Refractive Index: 1.708
• Boiling Point: 437.281 °C at 760 mmHg
• PKA: 3.72±0.30(Predicted)
• Flash Point: 232.396 °C
• PSA: 74.60000
• Density: 1.455g/cm³
• LogP: 2.23620
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

2,7-Naphthalenedicarboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,7-Naphthalenedicarboxylic acid

There total 8 articles about 2,7-Naphthalenedicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

dimethyl 2,7-naphthalenedicarboxylate (2549-47-5) → naphthalene-2,7-dicarboxylic acid (2089-89-6)

Guidance literature:

With potassium hydroxide; In ethanol; water;

DOI:10.1021/jacs.7b07699

Reference yield: 77.0%

2,7-dibromonaphthalene (58556-75-5) + carbon dioxide (124-38-9,18923-20-1) → naphthalene-2,7-dicarboxylic acid (2089-89-6)

Guidance literature:

2,7-dibromonaphthalene; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -78 ℃;

carbon dioxide; In tetrahydrofuran; pentane; at -78 ℃;

DOI:10.1021/ja9721327

Reference yield:

2,7-dimethylnaphthalene (582-16-1) → naphthalene-2,7-dicarboxylic acid (2089-89-6)

Guidance literature:

With sodium dichromate; In water;

DOI:10.1246/bcsj.62.786

upstream raw materials:

2,7-naphthalenedicarbonitrile

naphthalene

isopropyl alcohol

2,7-dimethylnaphthalene

Downstream raw materials:

2-(benzyloxycarbonyl)aminomethyl-7-(t-butoxycarbonylaminomethyl)naphthalene

3-{7-[1-tert-butyl-1-hydroxy-3-(2-phenylethynyl-phenyl)-prop-2-ynyl]-naphthalen-2-yl}-4,4-dimethyl-1-(2-phenylethynyl-phenyl)-pent-1-yn-3-ol

2,7-bis-[1-tert-butyl-3-(2-phenylethynyl-phenyl)-prop-2-ynyl]-naphthalene

naphthalene

Refernces

• 1、 Gensini, Martina,Altamura, Maria,Dimoulas, Tula,Fedi, Valentina,Giannotti, Danilo,Giuliani, Sandro,Guidi, Antonio,Harmat, Nicholas J. S.,Meini, Stefania,Nannicini, Rossano,Pasqui, Franco,Tramontana, Manuela,Triolo, Antonio,Maggi, Carlo Alberto. "Modulation on C- and N-terminal moieties of a series of potent and selective linear tachykinin NK2 receptor antagonists". scheme or table. p. 65 - 78. Retrieved 2010/11/16.
• 2、 Tan, Wei Hua,Niino, Noriaki,Ishikura, Takahiro,Maruta, Aya,Yamamoto, Tatsuyuki,Matsui, Yoshihisa. "Molecular Recognition of Naphthalenedicarboxylic Acid Regioisomers by Cyclodextrins". . p. 1285 - 1292. Retrieved 2007/10/03.