methyl 1-13C-2-thiophenyl acetate

Base Information

• Chemical Name: methyl 1-13C-2-thiophenyl acetate
• CAS No.: 169518-57-4
• Molecular Formula: C₉H₁₀O₂S
• Molecular Weight: 183.232
• Mol file: 169518-57-4.mol

Synonyms:methyl 1-13C-2-thiophenyl acetate

Chemical Property of methyl 1-13C-2-thiophenyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of methyl 1-13C-2-thiophenyl acetate

There total 1 articles about methyl 1-13C-2-thiophenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + ethyl (1-13C)-bromoacetate (61203-71-2) + thiophenol (108-98-5) → methyl 1-13C-2-thiophenyl acetate (169518-57-4)

Guidance literature:

With sodium methylate; Yield given. Multistep reaction; 1.) RT, 30 min, 2.) reflux, 40 min;

DOI:10.1002/jlcr.2580360707

Reference yield: 94.0%

methyl 1-13C-2-thiophenyl acetate (169518-57-4) → 2-13C-2-thiophenyl ethanol (169518-58-5)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 - 20 ℃;

DOI:10.1002/jlcr.2580360707

Reference yield:

methyl 1-13C-2-thiophenyl acetate (169518-57-4) → 1-13C-2-chloroethyl phenyl sulfide

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / LiAlH₄ / diethyl ether / 0 - 20 °C

2: SOCl₂ / CH₂Cl₂ / 2 h / Ambient temperature

With lithium aluminium tetrahydride; thionyl chloride; In diethyl ether; dichloromethane;

DOI:10.1002/jlcr.2580360707

upstream raw materials:

methanol

ethyl (1-13C)-bromoacetate

thiophenol

Downstream raw materials:

2-13C-2-thiophenyl ethanol