1-N-Cbz-3-pyrrolidinone

Base Information Edit

Chemical Name:1-N-Cbz-3-pyrrolidinone
CAS No.:130312-02-6
Molecular Formula:C12H13NO3
Molecular Weight:219.24
Hs Code.:29339900
European Community (EC) Number:672-436-5
DSSTox Substance ID:DTXSID80340057
Nikkaji Number:J1.185.780I
Wikidata:Q72516466
Mol file:130312-02-6.mol

Synonyms:1-N-Cbz-3-pyrrolidinone;130312-02-6;benzyl 3-oxopyrrolidine-1-carboxylate;1-Cbz-3-pyrrolidinone;N-Cbz-3-Pyrrolidinone;1-BENZYLOXYCARBONYL-3-PYRROLIDINONE;N-Benzyloxycarbonyl-3-pyrrolidinone;1-Z-3-Pyrrolidinone;1-Pyrrolidinecarboxylic acid, 3-oxo-, phenylmethyl ester;MFCD03001711;1-Carbobenzoxy-3-pyrrolidone;SCHEMBL265902;1-Carbobenzoxy-3-pyrrolidinone;1-Z-3-Pyrrolidinone, 96%;DTXSID80340057;1-Benzyloxycarbonyl-3-pyrrolidone;BCP17530;N-(Benzyloxycarbonyl)-3-pyrrolidone;N-benzyloxycarbonyl-pyrrolidin-3-one;AC-216;AKOS005146148;benzyl 3-oxo-1-pyrrolidine carboxylate;CS-W002982;FS-1280;PB23318;Benzyl 3-oxo-1-pyrrolidinecarboxylate #;SY001206;phenylmethyl 3-oxo-1-pyrrolidinecarboxylate;AM20060260;C2437;FT-0630056;FT-0695171;EN300-93818;3-Oxo-1-pyrrolidinecarboxylic acid benzyl ester;3-Oxopyrrolidine-1-carboxylic acid benzyl ester;3-oxo-pyrrolidine-1-carboxylic acid benzyl ester;3-Oxo-pyrrolidine-1-carboxylic acid, benzyl ester;W-205323

Suppliers and Price of 1-N-Cbz-3-pyrrolidinone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
1-Carbobenzoxy-3-pyrrolidone >98.0%(GC)
1g
$ 39.00

TCI Chemical
1-Carbobenzoxy-3-pyrrolidone >98.0%(GC)
5g
$ 194.00

SynQuest Laboratories
Pyrrolidin-3-one, N-Cbz protected
25 g
$ 300.00

SynQuest Laboratories
Pyrrolidin-3-one, N-Cbz protected
1 g
$ 55.00

SynQuest Laboratories
Pyrrolidin-3-one, N-Cbz protected
5 g
$ 90.00

Sigma-Aldrich
1-Z-3-Pyrrolidinone 96%
5g
$ 87.20

Sigma-Aldrich
1-Z-3-Pyrrolidinone 96%
1g
$ 69.30

Oakwood
1-N-Cbz-3-pyrrolidinone 96%
25g
$ 90.00

Oakwood
1-N-Cbz-3-pyrrolidinone 96%
5g
$ 29.00

Oakwood
1-N-Cbz-3-pyrrolidinone 96%
1g
$ 10.00

Total 84 raw suppliers

Chemical Property of 1-N-Cbz-3-pyrrolidinone Edit

Chemical Property:

Vapor Pressure:1.13E-05mmHg at 25°C
Melting Point:45-47 ºC
Refractive Index:n20/D 1.5410
Boiling Point:370.2 ºC at 760 mmHg
PKA:-1.84±0.20(Predicted)
Flash Point:177.7 ºC
PSA：46.61000
Density:1.255 g/cm³
LogP:1.53590
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:soluble in Methanol
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:219.08954328
Heavy Atom Count:16
Complexity:271

Purity/Quality:

99% ^*data from raw suppliers

1-Carbobenzoxy-3-pyrrolidone >98.0%(GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-40
Safety Statements: 23-24/25-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CC1=O)C(=O)OCC2=CC=CC=C2

Technology Process of 1-N-Cbz-3-pyrrolidinone

There total 15 articles about 1-N-Cbz-3-pyrrolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 95656-88-5
benzyl 3-hydroxypyrrolidine-1-carboxylate

: 130312-02-6
benzyl 3-oxopyrrolidine-1-carboxylate

Guidance literature:: benzyl 3-hydroxypyrrolidine-1-carboxylate; With pyridine-SO₃ complex; N-ethyl-N,N-diisopropylamine; In dichloromethane; dimethyl sulfoxide; at 0 ℃; for 1h;

With water; In dichloromethane; dimethyl sulfoxide;

Reference yield: 88.0%

: 100858-32-0
(S)-3-hydroxy-1-pyrrolidinecarboxylic acid phenylmethyl ester

: 130312-02-6
benzyl 3-oxopyrrolidine-1-carboxylate

Guidance literature:: With tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide; In dichloromethane; for 2h; Molecular sieve; Inert atmosphere;