2-Chloro-N4-isobutylquinoline-3,4-diamine

Base Information

Chemical Name:2-Chloro-N4-isobutylquinoline-3,4-diamine
CAS No.:133860-76-1
Molecular Formula:C13H16ClN3
Molecular Weight:249.743
Hs Code.:2933499090
European Community (EC) Number:603-770-1
DSSTox Substance ID:DTXSID10471808
Wikidata:Q72455550
Mol file:133860-76-1.mol

Synonyms:133860-76-1;2-Chloro-N4-isobutylquinoline-3,4-diamine;2-chloro-3-amino-4-(2-methylpropylamino)quinoline;2-Chloro-N4-(2-methypropyl)-3,4-quinolinediamine;2-Chloro-N4-(2-methylpropyl)-3,4-quinolinediamine;2-chloro-4-N-(2-methylpropyl)quinoline-3,4-diamine;3-amino-2-chloro-4-[(2-methylpropyl)amino]quinoline;3,4-Quinolinediamine, 2-chloro-N4-(2-methylpropyl)-;2-chloro-3-amino-4-[N-(2-methylpropyl)]amino quinoline;SCHEMBL843109;DTXSID10471808;JARNINMUMFRNPS-UHFFFAOYSA-N;AKOS015914452;AC-18442;AC-31131;FT-0643207;A806692;2-chloro-N4-(2-methylpropyl)quinoline-3,4-diamine;J-006444;2-Chloro-N~4~-(2-methylpropyl)quinoline-3,4-diamine;2-chloro-N4 -(2-methylpropyl)-3,4-quinolinediamine

Suppliers and Price of 2-Chloro-N4-isobutylquinoline-3,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Chloro-N4-isobutylquinoline-3,4-diamine 95+%
1g
$ 353.00

Chemenu
2-chloro-N4-isobutylquinoline-3,4-diamine 95%
1g
$ 333.00

Biosynth Carbosynth
2-Chloro-3-amino-4-(2-methylpropylamino)quinoline
5 g
$ 431.00

Biosynth Carbosynth
2-Chloro-3-amino-4-(2-methylpropylamino)quinoline
10 g
$ 750.00

American Custom Chemicals Corporation
2-CHLORO-3-AMINO-4-ISOBUTYL AMINO QUINOLINE 95.00%
5G
$ 1212.75

Alichem
2-Chloro-N4-isobutylquinoline-3,4-diamine
1g
$ 400.00

AK Scientific
2-Chloro-N4-isobutylquinoline-3,4-diamine
10g
$ 1062.00

AHH
2-Chloro-3-amino-4-(2-methylpropylamino)quinoline 98%
25g
$ 703.00

Total 41 raw suppliers

Chemical Property of 2-Chloro-N4-isobutylquinoline-3,4-diamine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.669
Boiling Point:395.724 °C at 760 mmHg
Flash Point:193.127 °C
PSA：50.94000
Density:1.246 g/cm³
LogP:4.19250
Storage Temp.:2-8°C
XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:249.1032752
Heavy Atom Count:17
Complexity:247

Purity/Quality:

99.9% ^*data from raw suppliers

2-Chloro-N4-isobutylquinoline-3,4-diamine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CNC1=C(C(=NC2=CC=CC=C21)Cl)N

Technology Process of 2-Chloro-N4-isobutylquinoline-3,4-diamine

There total 5 articles about 2-Chloro-N4-isobutylquinoline-3,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 133860-75-0
2-chloro-N⁴-(2-methylpropyl)-3-nitroquinoline-4-amine

: 133860-76-1
2-chloro-N⁴-(2-methylpropyl)quinoline-3,4-diamine

Guidance literature:: With iron; ammonium chloride; In ethanol; water; at 70 ℃; for 3h;
DOI:10.1016/j.bioorg.2020.104293

Reference yield:

: 132521-66-5
2,4-dichloro-3-nitroquinoline

: 133860-76-1
2-chloro-N⁴-(2-methylpropyl)quinoline-3,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 17.8 g / Et₃N / CH₂Cl₂ / 0.5 h / Heating

2: H₂; MgSO₄ / Pt/C / ethyl acetate / 2585.74 Torr

With hydrogen; magnesium sulfate; triethylamine; platinum on activated charcoal; In dichloromethane; ethyl acetate;
DOI:10.1021/jm049211v

Reference yield:

: 15151-57-2
4-hydroxy-3-nitro-1,2-dihydroquinolin-2-one

: 133860-76-1
2-chloro-N⁴-(2-methylpropyl)quinoline-3,4-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: POCl₃; Et₃N / toluene / 4 h / 80 - 90 °C

2: 17.8 g / Et₃N / CH₂Cl₂ / 0.5 h / Heating

3: H₂; MgSO₄ / Pt/C / ethyl acetate / 2585.74 Torr

With hydrogen; magnesium sulfate; triethylamine; trichlorophosphate; platinum on activated charcoal; In dichloromethane; ethyl acetate; toluene;
DOI:10.1021/jm049211v