2-(S-t-butylsulfanylmethyl)-3-(3-bromophenyl)propionic acid

Base Information

• Chemical Name: 2-(S-t-butylsulfanylmethyl)-3-(3-bromophenyl)propionic acid
• CAS No.: 1162122-11-3
• Molecular Formula: C₁₄H₁₉BrO₂S
• Molecular Weight: 331.274
• Mol file: 1162122-11-3.mol

Synonyms:2-(S-t-butylsulfanylmethyl)-3-(3-bromophenyl)propionic acid

Chemical Property of 2-(S-t-butylsulfanylmethyl)-3-(3-bromophenyl)propionic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-(S-t-butylsulfanylmethyl)-3-(3-bromophenyl)propionic acid

There total 2 articles about 2-(S-t-butylsulfanylmethyl)-3-(3-bromophenyl)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

2-sulfanylmethyl-3-(3-bromophenyl)propionic acid (1162122-10-2) + C20H20Br2O4S2 + tert-butyl alcohol (75-65-0) → 2-(S-t-butylsulfanylmethyl)-3-(3-bromophenyl)propionic acid (1162122-11-3)

Guidance literature:

With hydrogenchloride; In water; for 4h; Heating / reflux;

Reference yield:

2-sulfanylmethyl-3-(3-bromophenyl)propionic acid (1162122-10-2) + tert-butyl alcohol (75-65-0) → 2-(S-t-butylsulfanylmethyl)-3-(3-bromophenyl)propionic acid (1162122-11-3)

Guidance literature:

With hydrogenchloride; In water; for 4h; Reflux;

DOI:10.1002/jlcr.1566

Reference yield: 79.0%

2-(S-t-butylsulfanylmethyl)-3-(3-bromophenyl)propionic acid (1162122-11-3) + benzyl 2-aminoacetate hydrochloride (2462-31-9) → 2-[3-(3-bromophenyl)-2-(S-t-butylsulfanylmethyl)propionylamino]acetic acid benzyl ester (1162122-12-4)

Guidance literature:

With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; at 0 - 20 ℃;

DOI:10.1002/jlcr.1566

upstream raw materials:

2-sulfanylmethyl-3-(3-bromophenyl)propionic acid

tert-butyl alcohol

Downstream raw materials:

2-benzyl-3-(tert-butylthio)propionic acid

2-[3-(3-bromophenyl)-2-(S-t-butylsulfanylmethyl)propionylamino]acetic acid benzyl ester