1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Base Information

Chemical Name:1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione
CAS No.:95782-35-7
Molecular Formula:C₃₆H₄₉N₃O₈S₂Si
Molecular Weight:744.018
Hs Code.:

Synonyms:1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Suppliers and Price of 1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

There total 4 articles about 1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 124-63-0
methanesulfonyl chloride

: 95694-62-5
1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-(hydroxymethyl)-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

: 95782-35-7
1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Guidance literature:: With triethylamine; In tetrahydrofuran; for 0.583333h; Ambient temperature;
DOI:10.1021/ja00297a035

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 95782-35-7
1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / Et₃N / tetrahydrofuran / 14 h / Ambient temperature

2: 75 percent / Et₃N / tetrahydrofuran / 0.58 h / Ambient temperature

With triethylamine; In tetrahydrofuran;
DOI:10.1021/ja00297a035

Reference yield:

: 95782-44-8
syn-1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-(hydroxymethyl)-3''-(hydroxypropyl)>-2,5-piperazinedione (minor diastereomer)

: 95782-35-7
1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-6-<1''-<((methylsulfonyl)oxy)methyl>-3''-<((tert-butyldimethylsilyl)oxy)propyl>>-2,5-piperazinedione

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / Et₃N / tetrahydrofuran / 14 h / Ambient temperature

2: 75 percent / Et₃N / tetrahydrofuran / 0.58 h / Ambient temperature

With triethylamine; In tetrahydrofuran;
DOI:10.1021/ja00297a035