methyl 2-(2,2-dimethylpropionylamino)-4-fluoro-6-prop-2-ynyloxybenzoate

Base Information

Chemical Name:methyl 2-(2,2-dimethylpropionylamino)-4-fluoro-6-prop-2-ynyloxybenzoate
CAS No.:1609122-77-1
Molecular Formula:C₁₆H₁₈FNO₄
Molecular Weight:307.322
Hs Code.:

Synonyms:methyl 2-(2,2-dimethylpropionylamino)-4-fluoro-6-prop-2-ynyloxybenzoate

Suppliers and Price of methyl 2-(2,2-dimethylpropionylamino)-4-fluoro-6-prop-2-ynyloxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-(2,2-dimethylpropionylamino)-4-fluoro-6-prop-2-ynyloxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-(2,2-dimethylpropionylamino)-4-fluoro-6-prop-2-ynyloxybenzoate

There total 6 articles about methyl 2-(2,2-dimethylpropionylamino)-4-fluoro-6-prop-2-ynyloxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1609122-78-2
methyl 2-(2,2-dimethylpropionylamino)-4-fluoro-6-hydroxybenzoate

: 106-96-7
propargyl bromide

: 1609122-77-1
methyl 2-(2,2-dimethylpropionylamino)-4-fluoro-6-prop-2-ynyloxybenzoate

Guidance literature:: With potassium carbonate; In acetone; toluene; for 20h; Reflux;

Reference yield:

: 3282-30-2
pivaloyl chloride

: 1609122-77-1
methyl 2-(2,2-dimethylpropionylamino)-4-fluoro-6-prop-2-ynyloxybenzoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: pyridine / 1,4-dioxane / 21 h / 20 - 85 °C

1.2: 2 h / 20 °C

2.1: lithium tert-butoxide / dimethyl sulfoxide / 0.08 h / 80 °C

2.2: 20 h / 80 °C / Inert atmosphere

3.1: diazomethyl-trimethyl-silane / toluene; diethyl ether / 2 h / 0 - 20 °C / Inert atmosphere

4.1: 20% palladium hydroxide-activated charcoal; hydrogen; acetic acid / ethyl acetate / 25 h / 20 °C / Inert atmosphere

5.1: potassium carbonate / toluene; acetone / 20 h / Reflux

With pyridine; 20% palladium hydroxide-activated charcoal; hydrogen; potassium carbonate; acetic acid; lithium tert-butoxide; diazomethyl-trimethyl-silane; In 1,4-dioxane; diethyl ether; dimethyl sulfoxide; ethyl acetate; acetone; toluene;

Reference yield:

: 1609122-79-3
methyl 2-benzyloxy-6-(2,2-dimethylpropionylamino)-4-fluorobenzoate

: 1609122-77-1
methyl 2-(2,2-dimethylpropionylamino)-4-fluoro-6-prop-2-ynyloxybenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 20% palladium hydroxide-activated charcoal; hydrogen; acetic acid / ethyl acetate / 25 h / 20 °C / Inert atmosphere

2: potassium carbonate / toluene; acetone / 20 h / Reflux

With 20% palladium hydroxide-activated charcoal; hydrogen; potassium carbonate; acetic acid; In ethyl acetate; acetone; toluene;