Technology Process of 2-ethyl-2-(4-methoxyphenyl)butanoic acid
There total 3 articles about 2-ethyl-2-(4-methoxyphenyl)butanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene;
In
water; tert-butyl alcohol;
at 20 ℃;
for 18h;
Cooling with ice;
DOI:10.1248/cpb.59.1376
- Guidance literature:
-
Multi-step reaction with 2 steps
1: diisobutylaluminium hydride / toluene / 16 h / 0 °C
2: sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene / water; tert-butyl alcohol / 18 h / 20 °C / Cooling with ice
With
sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; diisobutylaluminium hydride;
In
water; toluene; tert-butyl alcohol;
DOI:10.1248/cpb.59.1376
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 20 h / 20 °C / Cooling with ice
2: diisobutylaluminium hydride / toluene / 16 h / 0 °C
3: sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene / water; tert-butyl alcohol / 18 h / 20 °C / Cooling with ice
With
sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; sodium hydride; diisobutylaluminium hydride;
In
water; N,N-dimethyl-formamide; toluene; mineral oil; tert-butyl alcohol;
DOI:10.1248/cpb.59.1376
