(E)-1-(tert-Butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone

Base Information

• Chemical Name: (E)-1-(tert-Butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone
• CAS No.: 152452-56-7
• Molecular Formula: C₁₅H₂₂OSSi
• Molecular Weight: 278.491
• Mol file: 152452-56-7.mol

Synonyms:(E)-1-(tert-Butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone

Chemical Property of (E)-1-(tert-Butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-(tert-Butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone

There total 1 articles about (E)-1-(tert-Butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

4-(tert-butyl-dimethyl-silanyl)-4-hydroxy-6-phenylsulfanyl-hex-5-en-2-one (416893-36-2) → (E)-1-(tert-Butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone (152452-56-7) + 1-(tert-butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone (152452-57-8) + 4-(tert-butyl-dimethyl-silanyloxy)-6-phenylsulfanyl-hex-4-en-2-one + (1R,2R)-4-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-2-phenylsulfanyl-cyclopent-3-enol

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -80 ℃; for 0.166667h;

DOI:10.1021/jo0160219

Reference yield: 76.0%

acetic acid tert-butyl ester (540-88-5) + (E)-1-(tert-Butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone (152452-56-7) → tert-bytyl (E)-3-tert-butyl(dimethyl)silyl-3-hydroxy-5-phenylthio-4-pentenoate (211386-13-9)

Guidance literature:

acetic acid tert-butyl ester; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -80 ℃; for 30h;

(E)-1-(tert-Butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone; In tetrahydrofuran; hexane; Further stages.;

DOI:10.1021/jo0160219

Reference yield: 68.0%

acetone (67-64-1) + (E)-1-(tert-Butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone (152452-56-7) → (1R,2R)-4-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-2-phenylsulfanyl-cyclopent-3-enol

Guidance literature:

acetone; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -80 ℃; for 0.25h;

(E)-1-(tert-Butyl-dimethyl-silanyl)-3-phenylsulfanyl-propenone; In tetrahydrofuran; hexane; at -80 - -30 ℃; Further stages.;

DOI:10.1021/jo0160219

upstream raw materials:

4-(tert-butyl-dimethyl-silanyl)-4-hydroxy-6-phenylsulfanyl-hex-5-en-2-one

Downstream raw materials:

tert-bytyl (E)-3-tert-butyl(dimethyl)silyl-3-hydroxy-5-phenylthio-4-pentenoate

4-(tert-butyl-dimethyl-silanyl)-4-hydroxy-6-phenylsulfanyl-hex-5-en-2-one