4-aminophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside

Base Information

• Chemical Name: 4-aminophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside
• CAS No.: 135253-84-8
• Molecular Formula: C₃₂H₄₁NO₁₈
• Molecular Weight: 727.673
• Mol file: 135253-84-8.mol

Synonyms:4-aminophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside

Chemical Property of 4-aminophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-aminophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside

There total 10 articles about 4-aminophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

4-nitrophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside (84034-75-3) → 4-aminophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside (135253-84-8,60515-61-9)

Guidance literature:

With hydrogen; palladium(II) hydroxide; In methanol; dichloromethane; for 4h;

DOI:10.1039/c6ob01712f

Reference yield:

2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide (4753-07-5) → 4-aminophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside (135253-84-8,60515-61-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 57 percent / tetrabutylammonium hydrogen sulphate (TBAHS), 1 M aq. NaOH / CH₂Cl₂ / 25 °C

2: ammonium formate / 10percent Pd/C / methanol / 0.08 h / Heating

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; ammonium formate; palladium on activated charcoal; In methanol; dichloromethane;

DOI:10.1039/c39910000536

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → 4-aminophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside (135253-84-8,60515-61-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 57 percent / tetrabutylammonium hydrogen sulphate (TBAHS), 1 M aq. NaOH / CH₂Cl₂ / 25 °C

2: ammonium formate / 10percent Pd/C / methanol / 0.08 h / Heating

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; ammonium formate; palladium on activated charcoal; In methanol; dichloromethane;

DOI:10.1039/c39910000536

upstream raw materials:

4-nitrophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside

4-nitro-phenol

2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide

lactose octaacetate

Downstream raw materials:

Acetic acid (2S,3R,4S,5R,6R)-3-acetoxy-6-acetoxymethyl-2-(4-acryloylamino-phenoxy)-5-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-4-yl ester

N-{4-[(2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-hydroxymethyl-5-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-phenyl}-acrylamide

p-(4-oxopentanamido)-phenyl β-D-lactose

5-(-N-(p-O-(2,3,6,2,3,4,6-Hepta-O-acetyl-β-lactosyl)phenyl)-aminocarbonyl)-2,2'-bipyridine